Rs737865
| Orientation | minus |
| is a | snp |
| is | mentioned by |
| dbSNP | rs737865 |
| PheGenI | rs737865 |
| nextbio | rs737865 |
| hapmap | rs737865 |
| 1000 genomes | rs737865 |
| hgdp | rs737865 |
| ensembl | rs737865 |
| gopubmed | rs737865 |
| geneview | rs737865 |
| scholar | rs737865 |
| rs737865 | |
| pharmgkb | rs737865 |
| gwascentral | rs737865 |
| openSNP | rs737865 |
| 23andMe | rs737865 |
| 23andMe all | rs737865 |
| SNP Nexus | |
| SNPshot | rs737865 |
| SNPdbe | rs737865 |
| MSV3d | rs737865 |
| Gene | COMT, TXNRD2 |
| Chromosome | 22 |
| Orientation | minus |
| Position | 19930121 |
| Reference | GRCh37.p2 37.2/134 |
| Max Magnitude |
| Geno | Mag | Summary |
|---|---|---|
| (A;G) |
| Make rs737865(C;C) |
| Make rs737865(C;T) |
| Make rs737865(T;T) |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
COMT haplotypes at rs737865 and rs165599 may predict a favorable outcome for bupropion treatment for smoking cessation.
We have typed the IVS 1 rs737865 and 3' rs615599 sites and also included a novel IVS 1 indel polymorphism. We report that the schizophrenia-associated haplotype is significantly heterogeneous in populations worldwide. [PMID 15098000]
may affect non-Hodgkin lymphoma, anxiety-related personality traits
Also mentioned in these PMIDs
[PMID 19369177] Association of the 3' Region of COMT with Schizophrenia in Taiwan
[PMID 19290789] Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment
[PMID 19077118] Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia
[PMID 21940152] The impact of COMT gene polymorphisms on suicidality in treatment resistant major depressive disorder - A European Multicenter Study
