Rs737865

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Orientationminus
Geno Mag Summary
(A;G)
Make rs737865(C;C)
Make rs737865(C;T)
Make rs737865(T;T)
ReferenceGRCh37.p2 37.2/134
Chromosome22
Position19930121
GeneCOMT, TXNRD2
is asnp
is mentioned by
dbSNPrs737865
Exacrs737865
PheGenIrs737865
nextbiors737865
hapmaprs737865
1000 genomesrs737865
hgdprs737865
ensemblrs737865
gopubmedrs737865
geneviewrs737865
scholarrs737865
googlers737865
pharmgkbrs737865
gwascentralrs737865
openSNPrs737865
23andMers737865
23andMe allrs737865
SNP Nexus

SNPshotrs737865
SNPdbers737865
MSV3drs737865
Max Magnitude
? (C;C) (C;T) (T;T) 28
part of a three marker haplotype rs737865-rs4680-rs165599

COMT haplotypes at rs737865 and rs165599 may predict a favorable outcome for bupropion treatment for smoking cessation.

We have typed the IVS 1 rs737865 and 3' rs615599 sites and also included a novel IVS 1 indel polymorphism. We report that the schizophrenia-associated haplotype is significantly heterogeneous in populations worldwide. [PMID 15098000]

may affect non-Hodgkin lymphoma, anxiety-related personality traits

Also mentioned in these PMIDs


[PMID 19369177] Association of the 3' Region of COMT with Schizophrenia in Taiwan


[PMID 19290789] Association studies of catechol-O-methyltransferase (COMT) gene with schizophrenia and response to antipsychotic treatment


[PMID 19077118] Genetic variants in COMT and neurocognitive impairment in families of patients with schizophrenia

OMIM104300
DescALZHEIMER DISEASE; AD
Variant
Relatedalso
OMIM116790
DescCATECHOL-O-METHYLTRANSFERASE; COMT
Variant
Relatedalso




[PMID 21940152] The impact of COMT gene polymorphisms on suicidality in treatment resistant major depressive disorder - A European Multicenter Study