rs7183877 is part of a haplotype spanning 166kB on chromosome 15, defined by 13 SNPs listed below, found in 97% of all Caucasians with blue eyes. In this haplotype, variations in rs1129038 and rs12913832 are relatively common in Caucasians though rare among other ethnic groups.[PMID 18172690] PMID 18252221] Three genome-wide association studies and a linkage analysis identify HERC2 as a human iris color gene.
[PMID 18483556] A genome-wide association study identifies novel alleles associated with hair color and skin pigmentation.
[PMID 20585627] Web-based, participant-driven studies yield novel genetic associations for common traits.