Rs279871

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Orientationminus
Make rs279871(A;A)
Make rs279871(A;G)
Make rs279871(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position46303716
GeneGABRA2
is asnp
is mentioned by
dbSNPrs279871
Exacrs279871
PheGenIrs279871
nextbiors279871
hapmaprs279871
1000 genomesrs279871
hgdprs279871
ensemblrs279871
gopubmedrs279871
geneviewrs279871
scholarrs279871
googlers279871
pharmgkbrs279871
gwascentralrs279871
openSNPrs279871
23andMers279871
23andMe allrs279871
SNP Nexus

SNPshotrs279871
SNPdbers279871
MSV3drs279871
GMAF0.4123
This SNP in the GABRA2 gene has been linked to Alcoholism.

The strongest association for this SNP is seen when it is a member of a haplotype consisting of the rs279871(A) + rs279845(T) + rs279836(A) alleles [PMID 15024690OA-icon.png].

OMIM137140
DescGAMMA-AMINOBUTYRIC ACID RECEPTOR, ALPHA-2; GABRA2
Variant
Relatedalso
[PMID 20698837OA-icon.png] A Polymorphism in GABRA2 Is Associated With the Medial Frontal Response to Alcohol Cues in an fMRI Study
OMIM137140
Desc
Variant0001
Relatedalso


[PMID 18005236] Human gamma-aminobutyric acid A receptor alpha2 gene moderates the acute effects of alcohol and brain mRNA expression.


[PMID 18634760OA-icon.png] Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes.


[PMID 18727688OA-icon.png] The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample.


[PMID 18781239OA-icon.png] Multiple-domain predictors of problematic alcohol use in young adulthood.


[PMID 19487630OA-icon.png] Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring.


[PMID 19783384OA-icon.png] Test of association between GABRA2 (SNP rs279871) and adolescent conduct/alcohol use disorders utilizing a sample of clinic referred youth with serious substance and conduct problems, controls and available first degree relatives.


[PMID 20133874OA-icon.png] Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.


[PMID 21683760] Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence.


[PMID 23974430] Gender-Specific Gene-Environment Interaction in Alcohol Dependence: The Impact of Daily Life Events and GABRA2


[PMID 22817768OA-icon.png] Voluntary intravenous self-administration of alcohol detects an interaction between GABAergic manipulation and GABRG1 polymorphism genotype: a pilot study.