Rs279845

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Orientationplus
is asnp
is mentioned by
dbSNPrs279845
PheGenIrs279845
nextbiors279845
hapmaprs279845
1000 genomesrs279845
hgdprs279845
ensemblrs279845
gopubmedrs279845
geneviewrs279845
scholarrs279845
googlers279845
pharmgkbrs279845
gwascentralrs279845
openSNPrs279845
23andMers279845
23andMe allrs279845
SNP Nexus

SNPshotrs279845
SNPdbers279845
MSV3drs279845
GeneGABRA2
Chromosome4
Orientationplus
GMAF0.4412
Position46327706
ReferenceGRCh38 38.1/141
Max Magnitude
Make rs279845(A;A)
Make rs279845(A;T)
Make rs279845(T;T)
? (A;A) (A;T) (T;T) 28
This SNP in the GABRA2 gene has been linked to Alcoholism.

The strongest association for this SNP is seen when it is a member of a haplotype consisting of the rs279871(A) + rs279845(T) + rs279836(A) alleles [PMID 15024690OA-icon.png].

OMIM137140
DescGAMMA-AMINOBUTYRIC ACID RECEPTOR, ALPHA-2; GABRA2
Variant
Relatedalso
OMIM137140
Desc
Variant0002
Relatedalso
[PMID 22501025OA-icon.png] GABRA2 markers moderate the subjective effects of alcohol

[PMID 18634760OA-icon.png] Uncovering genes for cognitive (dys)function and predisposition for alcoholism spectrum disorders: a review of human brain oscillations as effective endophenotypes.

[PMID 18727688OA-icon.png] The role of GABRA2 in alcohol dependence, smoking, and illicit drug use in an Australian population sample.

[PMID 19487630OA-icon.png] Role of GABRA2 in trajectories of externalizing behavior across development and evidence of moderation by parental monitoring.

[PMID 20133874OA-icon.png] Cocaine effects on mouse incentive-learning and human addiction are linked to alpha2 subunit-containing GABAA receptors.


[PMID 22555154] Gamma-aminobutyric acid A receptor, alpha-2 (GABRA2) variants as individual markers for alcoholism: a meta-analysis.