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{{ population diversity | geno1=(C;C) | geno2=(C;T) | geno3=(T;T) | CEU | 67.9 | 28.6 | 3.6 | HCB | 52.2 | 39.7 | 8.1 | JPT | 76.1 | 22.1 | 1.8 | YRI | 77.9 | 22.1 | 0.0 | ASW | 86.0 | 14.0 | 0.0 | CHB | 52.2 | 39.7 | 8.1 | CHD | 61.1 | 34.3 | 4.6 | GIH | 53.5 | 38.6 | 7.9 | LWK | 72.2 | 26.9 | 0.9 | MEX | 70.7 | 29.3 | 0.0 | MKK | 77.5 | 20.5 | 2.0 | TSI | 67.6 | 29.4 | 2.9 | HapMapRevision=28 }}[[rs27072]], a SNP in the dopamine transporter [[SLC6A3]] gene, has been associated with more severe symptoms upon alcohol withdrawal, such as seizures, in a study of 250 Caucasian alcohol-dependent patients. Two haplotypes appear to be tagged by this SNP and a neighbor, [[rs27048]]. The rs27072 polymorphism has been shown to be significantly associated with [[ADHD]] in clinical samples of Canadian children aged 6 to 16 [Feng et al., 2005] and the significant association was also reported by Ouellet-Morin et al. in a Canadian twin study, 2008 (Am. J. of Medical Genetics Part B, 147B:1442-1449 (2008). {{PMID|18070248}} {{omim |desc=ATTENTION DEFICIT-HYPERACTIVITY DISORDER; ADHD |id=143465 |rsnum=27072 }} {{omim |desc=SOLUTE CARRIER FAMILY 6 (NEUROTRANSMITTER TRANSPORTER, DOPAMINE), |id=126455 |rsnum=27072 }} {{PMID|19740369}}The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-olds. {{PMID|19879111}}Association of promoter variants of human dopamine transporter gene with schizophrenia in Han Chinese. {{PMID|21525861}}Dopamine Transporter Gene Variant Affecting Expression in Human Brain is Associated with Bipolar Disorder. {{PMID|16082693}}Sequence variation in the 3'-untranslated region of the dopamine transporter gene and attention-deficit hyperactivity disorder (ADHD). {{PMID|18165969}}Association of the dopamine transporter gene and ADHD symptoms in a Canadian population-based sample of same-age twins. {{PMID|19506906}}Candidate gene studies of ADHD: a meta-analytic review. {{PMID|14685824}} Association between polymorphism of the dopamine transporter gene and early smoking onset: an interaction risk on nicotine dependence. {{PMID|18690117}} Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. {{PMID|19693267}} Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gene. {{PMID|20505557}} Haplotypes of dopamine and serotonin transporter genes are associated with antisocial personality disorder in alcoholics. {{PMID|20580759}} Pharacogenetic effects of dopamine transporter gene polymorphisms on response to chlorpromazine and clozapine and on extrapyramidal syndrome in schizophrenia. {{PMID|21354244}} The role of dopamine transporter (SLC6A3) and dopamine D2 receptor/ankyrin repeat and kinase domain containing 1 (DRD2/ANKK1) gene polymorphisms in personality traits. [[Alcohol Dependence]] {{PMID Auto |PMID=23340505 |Title=Dopamine transporter DAT and receptor DRD2 variants affect risk of lethal cocaine abuse: a gene-gene-environment interaction }} {{on chip | 23andMe v1}} {{on chip | 23andMe v2}} {{on chip | 23andMe v3}} {{on chip | FTDNA2}} {{on chip | HumanOmni1Quad}} {{on chip | Illumina Human 1M}}
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