Promethease 0.1.82
Rs1800401
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs1800401 |
| hapmap | rs1800401 |
| hgdp | rs1800401 |
| ensembl | rs1800401 |
| gopubmed | rs1800401 |
| scholar | rs1800401 |
| rs1800401 | |
| pharmgkb | rs1800401 |
| hgvbaseg2p | rs1800401 |
| medrefsnp | rs1800401 |
| 23andMe | rs1800401 |
| SNP Nexus |
| Gene | OCA2 |
| Chromosome | 15 |
| Orientation | minus |
| Position | 25933648 |
| Genotype | Effect |
|---|---|
| rs1800401(C;C) | blue/gray eyes possible |
| rs1800401(C;T) | brown/black eyes more likely |
| rs1800401(T;T) | brown/black eyes more likely |
| Genotypes | Magnitude | Summary |
|---|---|---|
| Rs1800401(C;C) | blue/gray eyes possible | |
| Rs1800401(C;T) | brown/black eyes more likely | |
| Rs1800401(G;G) | 00 | |
| Rs1800401(T;T) | brown/black eyes more likely |
rs1800401 is located in exon 7 of the OCA2 gene at amino acid position 305. The (T) allele encodes the amino acid tryptophan (instead of arginine), and it is one of several SNPs associated with increased odds of having brown or black eye color in Caucasians. One copy of of rs1800401(T) is sufficient for this effect. [PMID 12163334, PMID 15889046; OMIM 203200.0011]
