Rs17036314

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Orientationplus
Geno Mag Summary
(C;C) risk of progressing from IGT to T2D; reduced by exercise
(C;G) risk of progressing from IGT to T2D; reduced by exercise
(G;G) normal
ReferenceGRCh37 37.1/131
Chromosome3
Position12376745
GenePPARG
is asnp
is mentioned by
dbSNPrs17036314
PheGenIrs17036314
nextbiors17036314
hapmaprs17036314
1000 genomesrs17036314
hgdprs17036314
ensemblrs17036314
gopubmedrs17036314
geneviewrs17036314
scholarrs17036314
googlers17036314
pharmgkbrs17036314
gwascentralrs17036314
openSNPrs17036314
23andMers17036314
23andMe allrs17036314
SNP Nexus

SNPshotrs17036314
SNPdbers17036314
MSV3drs17036314
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs17036314 is a SNP in the peroxisome proliferator-activated receptor gamma PPARG gene.

In a 4 year study of 479 overweight individuals with impaired glucose tolerance (IGT) who participated in the Finnish Diabetes Prevention Study (DPS), carrying a rs17036314(C) allele predicted conversion to type-2 diabetes (T2D) after adjustment for baseline fasting glucose (p=0.030). Increased physical activity reduced this risk.[PMID 18091023]