Promethease 0.1.82
Rs1044396
From SNPedia
| is a | snp |
| is | mentioned by |
| dbSNP | rs1044396 |
| hapmap | rs1044396 |
| hgdp | rs1044396 |
| ensembl | rs1044396 |
| gopubmed | rs1044396 |
| scholar | rs1044396 |
| rs1044396 | |
| pharmgkb | rs1044396 |
| hgvbaseg2p | rs1044396 |
| medrefsnp | rs1044396 |
| 23andMe | rs1044396 |
| SNP Nexus |
| Gene | CHRNA4 |
| Chromosome | 20 |
| Orientation | minus |
| Position | 61451578 |
| Genotype | Effect |
|---|---|
| rs1044396(C;C)* | ? |
| rs1044396(C;T)* | ? |
| rs1044396(T;T)* | ? |
g2b2mh blog rs1044396 mediates effects of nicotine self-medication via parietal cortex. subjects with the (T;T) genotype showed robust brain activity in the parietal cortex while subjects with the (C;C) genotype showed very little change in activity.
| Neighbor | rs28931591 |
| Distance | 778 |
| ? | (C;C) (C;T) (T;T) |
|---|---|
|
| |
Related to CHOLINERGIC RECEPTOR, NEURONAL NICOTINIC, ALPHA POLYPEPTIDE 4; CHRNA4
according to omim 118504. See also
| PharmGKB | PA164924603 |
| Name | |
| Annotation | This variant is closely linked to rs2236196 and has been associated with the intensification of nicotine dependence. |
| Gene | CHRNA4 |
| Featue | |
| Evidence | PubMed ID:19290018 |
| Drugs | nicotine |
| Diseases | Tobacco Use Disorder |
| Curation Level | Curated |
