From SNPedia
rs10246939 is one of three SNPs that form the main haplotypes behind the ability to perceive as bitter the
taste of the compound phenylthiocarbamide (PTC) and similar molecules in foods (like cabbage and raw broccoli) or drinks (like coffee and dark beers).
The rs10246939(C) allele, in the orientation shown in dbSNP, is the "tasting" allele, and it is dominant to the "non-tasting" allele rs10246939(T), so having one copy is enough to have the bitter tasting ability. If you are a "taster", you're also likely to carry at least one rs713598(G) and one rs1726866(C) allele since, along with rs10246939(C), these three SNPs form the most common tasting haplotype. If you lack these alleles, you're quite likely (~80%) to be a non-taster of bitterness, meaning that foods that may taste bitter to others taste far less bitter to you.[PMID 12595690]
| ? | (C;C) (C;T) (T;T) |
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Related to TASTE RECEPTOR, TYPE 2, MEMBER 38; TAS2R38
according to
omim 607751. See
also
