Rs1008805

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Orientationminus
is asnp
is mentioned by
dbSNPrs1008805
PheGenIrs1008805
nextbiors1008805
hapmaprs1008805
1000 genomesrs1008805
hgdprs1008805
ensemblrs1008805
gopubmedrs1008805
geneviewrs1008805
scholarrs1008805
googlers1008805
pharmgkbrs1008805
gwascentralrs1008805
openSNPrs1008805
23andMers1008805
23andMe allrs1008805
SNP Nexus

SNPshotrs1008805
SNPdbers1008805
MSV3drs1008805
GeneCYP19A1
Chromosome15
Orientationminus
GMAF0.3512
Position51257402
ReferenceGRCh38 38.1/141
Max Magnitude
Make rs1008805(C;C)
Make rs1008805(C;T)
Make rs1008805(T;T)
the presence of at least one G allele at rs1008805 was significantly associated with an increase in the risk of breast cancer (OR = 1.72 [95% CI, 1.20-2.49]), especially with estrogen and progesterone receptor negative breast cancer (OR = 3.89 [1.74-8.70] and OR = 2.52 [1.26-5.05], respectively).


[PMID 16949385] Aromatase gene (CYP 19) polymorphisms and endogenous androgen concentrations in a multiracial/multiethnic, multisite study of women at midlife.


[PMID 17975727] A CYP19 (aromatase) polymorphism is associated with increased premenopausal breast cancer risk.


[PMID 18199708OA-icon.png] Haplotype analyses of CYP19A1 gene variants and breast cancer risk: results from the Shanghai Breast Cancer Study.


[PMID 18622258OA-icon.png] Association of genetic polymorphisms in CYP19A1 and blood levels of sex hormones among postmenopausal Chinese women.


[PMID 18941913OA-icon.png] Coffee intake, variants in genes involved in caffeine metabolism, and the risk of epithelial ovarian cancer.


[PMID 19015200OA-icon.png] Polymorphisms in estrogen- and androgen-metabolizing genes and the risk of gastric cancer.


[PMID 19630952OA-icon.png] Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women.