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Gout

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Gout is a disease caused by a build-up of uric acid in the joints, provoking an arthritis-like inflammatory response. Wikipedia SNPs in several genes have been found in independent studies to be associated with increased risk of gout.


  • SLC17A3
    • rs1165205; the T allele appears to be protective against gout in the Framingham/Rotterdam study [PMID 18834626]. Note that 23andMe reports this as the A allele.

An intergenic SNP on chromosome 4, rs10489070, was associated with gout in both the Amish and Framingham/Rotterdam studies.