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Genoset

From SNPedia

A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.

Promethease understands this criteria syntax.

More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.

Most Significant

 ReputeMagnitudeSummaryModification date
This property is a special property in this wiki.
Gs14910testing for orientation issues8 May 2009 03:43:00
Gs2676APOE1/APOE111 October 2013 05:15:46
Gs216Bad62 copies of the APO-ε4 allele10 August 2014 21:44:23
Gs2286sickle cell affected25 October 2012 02:21:38
Gs1215DR3/4-DQ8 individual at high risk for type-1 diabetes21 October 2011 06:04:16
Gs2615Help us fix a bug in SNPedia30 July 2014 21:16:19
Gs254Bad4.1Pseudocholinesterase Deficiency25 October 2012 02:24:20
Gs1174risk of type-1 diabetes21 October 2011 06:04:12
Gs1134Haplogroup O38 January 2011 17:52:27
Gs219Bad4Hemochromatosis2 October 2014 19:13:37
... further results


Most Recently Active

 ReputeMagnitudeSummaryModification date
This property is a special property in this wiki.
Gs140Bad2NAT2 slow metabolizer23 May 2015 00:50:22
Gs234Bad1.7possible high pain sensitivity23 May 2015 00:18:20
Gs229Good3.6resistant to malaria, sickle cell carrier13 May 2015 13:26:52
Gs2413lighter green, brown or hazel eye color30 April 2015 23:54:03
Gs298Bad2.5Increased surveillance for colorectal cancer recommended16 April 2015 03:36:00
Gs2662.5Data Quality Warning24 March 2015 02:50:12
Gs162Bad3.3CYP2C9 Poor Metabolizers5 March 2015 14:46:46
Gs1961.6Haplogroup I (Y-DNA); 50% higher age-adjusted risk of coronary artery disease?3 March 2015 00:23:31
Gs224Bad3Two copies of GCH1 variant associated with lower levels of tetrahydrobiopterin21 February 2015 05:47:35
Gs291Good3Lower heart attack risk than average12 February 2015 02:46:01
... further results


You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.