Genoset

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A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.

Promethease understands this criteria syntax.

More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.

Most Significant

  Repute Magnitude Summary Modification dateThis property is a special property in this wiki.
Gs149 10 testing for orientation issues 8 May 2009 03:43:00
Gs267 6 APOE1/APOE1 11 October 2013 05:15:46
Gs216 Bad 6 2 copies of the APO-ε4 allele 10 August 2014 21:44:23
Gs228 6 sickle cell affected 25 October 2012 02:21:38
Gs261 5 Help us fix a bug in SNPedia 30 July 2014 21:16:19
Gs121 5 DR3/4-DQ8 individual at high risk for type-1 diabetes 21 October 2011 06:04:16
Gs254 Bad 4.1 Pseudocholinesterase Deficiency 25 October 2012 02:24:20
Gs113 4 Haplogroup O3 8 January 2011 17:52:27
Gs219 4 Hemochromatosis 21 October 2011 06:04:08
Gs268 Good 4 APOE E2/E2 6 December 2013 17:34:48
… further results


Most Recently Active

  Repute Magnitude Summary Modification dateThis property is a special property in this wiki.
Gs189 2.5 probably APOE E2/E4, but maybe E1/E3. E1 is the 'missing APOE allele' 15 September 2014 02:17:03
Gs216 Bad 6 2 copies of the APO-ε4 allele 10 August 2014 21:44:23
Gs256 2.5 Blue eyes 1 August 2014 11:39:11
Gs261 5 Help us fix a bug in SNPedia 30 July 2014 21:16:19
Gs141 Bad 3.5 2x risk of Alzheimer's disease 21 July 2014 18:47:00
Gs270 2 APOE E2/E4 or possibly E1/E3 21 July 2014 18:44:58
Gs269 Good 2 APOE E2/E3 21 July 2014 18:43:11
Gs246 Good 2 APOE3/APOE3 21 July 2014 18:40:41
Gs281 Bad 2.5 part of the 88% of the population claimed not to maintain weight loss unless you perform high energy exercise 20 July 2014 14:57:41
Gs191 Bad 3.1 problem metabolizing NSAIDs 19 July 2014 05:11:06
… further results


You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.