Genoset
A genoset refers to a defined set of genotypes; we have coined the term to represent the combination of alleles at 2 or more loci, especially when they are not contiguous along a chromosome. Typically, these are then related to a medical (or ancestral) consequence that arises only when a particular combination of SNPs is inherited.
Promethease understands this criteria syntax.
More information about genosets can be found in the related SNPedia blog post. Note that genosets themselves are boolean, not quantitative; each genoset is either true (present) or false (absent) in an individual, based on the genoset's criteria, in the same way that a genotype (or allele) is either present or absent. Note that if a DNA microarray platform lacks a given SNP, genosets that require it (that SNP) will not return a result during a Promethease evaluation.
Most Significant
| Repute | Magnitude | Summary | Modification dateThis property is a special property in this wiki. | |
|---|---|---|---|---|
| Gs149 | 10 | testing for orientation issues | 8 May 2009 03:43:00 | |
| Gs216 | Bad | 6 | 2 copies of the APO-ε4 allele | 22 February 2013 19:39:11 |
| Gs228 | 6 | sickle cell affected | 25 October 2012 02:21:38 | |
| Gs208 | 5 | Haplogroup I* (Y-DNA) | 23 January 2010 10:41:19 | |
| Gs261 | 5 | Help us fix a bug in SNPedia | 30 March 2013 19:25:46 | |
| Gs152 | 5 | CYP2C19 Poor Metabolizer | 21 October 2011 06:04:21 | |
| Gs121 | 5 | DR3/4-DQ8 individual at high risk for type-1 diabetes | 21 October 2011 06:04:16 | |
| Gs112 | 4.2 | Haplogroup I2 (Y-DNA) | 17 June 2011 23:19:22 | |
| Gs254 | Bad | 4.1 | Pseudocholinesterase Deficiency | 25 October 2012 02:24:20 |
| Gs117 | 4 | risk of type-1 diabetes | 21 October 2011 06:04:12 | |
| … further results | ||||
Most Recently Active
| Repute | Magnitude | Summary | Modification dateThis property is a special property in this wiki. | |
|---|---|---|---|---|
| Gs153 | 3.3 | CYP2C19 Extensive or Ultra-Fast Metabolizer | 8 May 2013 13:07:03 | |
| Gs193 | Bad | 4 | severe effects due to MTHFR polymorphisms affecting homocysteine? | 6 May 2013 17:31:58 |
| Gs259 | 2.5 | homozygous for eye color haplotype #3 | 29 April 2013 20:55:27 | |
| Gs255 | 2.3 | homozygous eye color haplotype #1 | 29 April 2013 20:53:42 | |
| Gs136 | Bad | 2 | Normal, but this haplotype in 8q24 increases risk of Prostate cancer | 28 April 2013 21:28:14 |
| Gs155 | Bad | 3 | CYP3A5 non-expressor | 28 April 2013 15:48:13 |
| Gs262 | 2 | R1b1a2a1a | 28 April 2013 12:21:59 | |
| Gs192 | Bad | 3.1 | MTHFR polymorphisms affecting homocysteine | 17 April 2013 14:46:28 |
| Gs145 | 4 | Female | 30 March 2013 19:29:56 | |
| Gs261 | 5 | Help us fix a bug in SNPedia | 30 March 2013 19:25:46 | |
| … further results | ||||
You can create a new genoset by clicking that link and filling in the form. But you'll still need to populate the criteria syntax.
