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SNPs in the region of the DRD2 gene have been studied in terms of their impact on the efficacy of the use of bupropion. In particular, rs1800497 may strongly influence whether Zyban helps a person stop smoking.
journal antipsychotics (Abilify, Risperdal, Seroquel), antidepressants (Prozac, Wellbutrin, Effexor, Paxil, Zoloft), anticonvulsants (Lamictal, Depakote, Trileptal, Klonopin, Topamax), and the stimulant (Concerta) metabolism affected by variations in CYP2C9, CYP2C19, and CYP2D6