rs9623117

plus

Geno	Mag	Summary
(C;C)		1.1x increased risk for prostate cancer
(C;T)		1.1x increased risk for prostate cancer
(T;T)		normal

Reference

GRCh38 38.1/141

Chromosome

22

Position

40056115

Gene

TNRC6B

is a	snp
is	mentioned by
dbSNP	rs9623117
dbSNP (classic)	rs9623117
ClinGen	rs9623117
ebi	rs9623117
HLI	rs9623117
Exac	rs9623117
Gnomad	rs9623117
Varsome	rs9623117
LitVar	rs9623117
Map	rs9623117
PheGenI	rs9623117
Biobank	rs9623117
1000 genomes	rs9623117
hgdp	rs9623117
ensembl	rs9623117
geneview	rs9623117
scholar	rs9623117
google	rs9623117
pharmgkb	rs9623117
gwascentral	rs9623117
openSNP	rs9623117
23andMe	rs9623117
SNPshot	rs9623117
SNPdbe	rs9623117
MSV3d	rs9623117
GWAS Ctlg	rs9623117

GMAF

0.3058

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 19117981 ] In seven different populations studied, rs9623117(C) was consistently higher in aggressive prostate cancer cases than in controls (p = 5.0 x 10e-7). The odds ratio (OR) of allele C for aggressive prostate cancer was estimated to be 1.18 (CI: 1.11-1.26). This SNP was also associated with increased risk for nonaggressive prostate cancer, with an odds ratio of 1.11 (CI: 1.04 - 1.19, p = 0.004).

[PMID 19434657 ] Individual and cumulative effect of prostate cancer risk-associated variants on clinicopathologic variables in 5,895 prostate cancer patients.

[PMID 19549807 ] Prostate cancer risk associated loci in African Americans.

[PMID 20690139] Meta-analysis of genome-wide and replication association studies on prostate cancer.

[PMID 25709475 ] Single-nucleotide polymorphisms of microRNA processing machinery genes and risk of colorectal cancer

[PMID 26203264 ] Single nucleotide polymorphisms of microRNA processing genes and outcome of non-Hodgkin's lymphoma

[PMID 29226993 ] Genetic polymorphisms of microRNA machinery genes predict overall survival of esophageal squamous carcinoma.