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rs910080

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs910080(A;G)
Make rs910080(G;G)
ReferenceGRCh38 38.1/141
Chromosome20
Position1979580
GeneLOC727993, PDYN
is asnp
is mentioned by
dbSNPrs910080
dbSNP (classic)rs910080
ClinGenrs910080
ebirs910080
HLIrs910080
Exacrs910080
Gnomadrs910080
Varsomers910080
LitVarrs910080
Maprs910080
PheGenIrs910080
Biobankrs910080
1000 genomesrs910080
hgdprs910080
ensemblrs910080
geneviewrs910080
scholarrs910080
googlers910080
pharmgkbrs910080
gwascentralrs910080
openSNPrs910080
23andMers910080
SNPshotrs910080
SNPdbers910080
MSV3drs910080
GWAS Ctlgrs910080
GMAF0.4669
Max Magnitude0
? (A;A) (A;G) (G;G) 28


[PMID 18923396OA-icon.png] In Caucasians, we found point-wise significant associations of 3' UTR SNPs (rs910080, rs910079, and rs2235749) with cocaine dependence and cocaine/alcohol codependence.



[PMID 19468819] Gene polymorphisms in prodynorphin (PDYN) are associated with episodic memory in the elderly


[PMID 21382455] Association between heroin dependence and prodynorphin gene polymorphisms


[PMID 22443215] Genetic association analyses of PDYN polymorphisms with heroin and cocaine addiction.


[PMID 23101464OA-icon.png] Association of the PDYN gene with alcohol dependence and the propensity to drink in negative emotional states


[PMID 27074815OA-icon.png] A Functional 3'UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits


[PMID 28656735] An analysis of genetic association in opioid dependence susceptibility.


ClinVar
Risk rs910080(G;G)
Alt rs910080(G;G)
Reference Rs910080(A;A)
Significance Non-pathogenic
Disease Spinocerebellar Ataxia
Variation info
Gene PDYN LOC727993
CLNDBN Spinocerebellar Ataxia, Dominant
Reversed 0
HGVS NC_000020.10:g.1960226A>G
CLNSRC
CLNACC RCV000263533.1,