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rs821577

From SNPedia

Orientationplus
Stabilizedplus
Make rs821577(G;G)
Make rs821577(G;T)
Make rs821577(T;T)
ReferenceGRCh38 38.1/141
Chromosome1
Position231931311
GeneDISC1, DISC1-IT1, TSNAX-DISC1
is asnp
is mentioned by
dbSNPrs821577
dbSNP (classic)rs821577
ClinGenrs821577
ebirs821577
HLIrs821577
Exacrs821577
Gnomadrs821577
Varsomers821577
LitVarrs821577
Maprs821577
PheGenIrs821577
Biobankrs821577
1000 genomesrs821577
hgdprs821577
ensemblrs821577
geneviewrs821577
scholarrs821577
googlers821577
pharmgkbrs821577
gwascentralrs821577
openSNPrs821577
23andMers821577
SNPshotrs821577
SNPdbers821577
MSV3drs821577
GWAS Ctlgrs821577
GMAF0.3783
Max Magnitude0
? (G;G) (G;T) (T;T) 28


[PMID 18317464] schizophrenia and bipolar disorder rs1538979 (P=0.016; odds ratio=2.73+/-95% confidence interval (CI) 1.42-5.27) and rs821577 (P=0.040; odds ratio=1.64+/-95% CI 1.23-2.19)


[PMID 21376542] The effects of DISC1 risk variants on brain activation in controls, patients with bipolar disorder and patients with schizophrenia

[PMID 15386212OA-icon.png] Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder.

[PMID 19188535OA-icon.png] Association of variants in DISC1 with psychosis-related traits in a large population cohort.

[PMID 19300510OA-icon.png] The DISC1 pathway modulates expression of neurodevelopmental, synaptogenic and sensory perception genes.

[PMID 19414483OA-icon.png] The DISC locus and schizophrenia: evidence from an association study in a central European sample and from a meta-analysis across different European populations.