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rs769449

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0
Make rs769449(A;A)
Make rs769449(A;G)
ReferenceGRCh38 38.1/141
Chromosome19
Position44906745
GeneAPOE
is asnp
is mentioned by
dbSNPrs769449
dbSNP (classic)rs769449
ClinGenrs769449
ebirs769449
HLIrs769449
Exacrs769449
Gnomadrs769449
Varsomers769449
LitVarrs769449
Maprs769449
PheGenIrs769449
Biobankrs769449
1000 genomesrs769449
hgdprs769449
ensemblrs769449
geneviewrs769449
scholarrs769449
googlers769449
pharmgkbrs769449
gwascentralrs769449
openSNPrs769449
23andMers769449
SNPshotrs769449
SNPdbers769449
MSV3drs769449
GWAS Ctlgrs769449
GMAF0.08219
Max Magnitude0
GWAS snp
PMID [PMID 18439548OA-icon.png]
Trait C-reactive protein
Title Loci Related to Metabolic-Syndrome Pathways Including LEPR, HNF1A, IL6R, and GCKR Associate with Plasma C-Reactive Protein: The Women's Genome Health Study
Risk Allele
P-val 8.9999999999999994E-21
Odds Ratio 0.26 [NR] mg/dl decrease


[PMID 18852197OA-icon.png] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.


[PMID 19802338OA-icon.png] Genetic loci associated with plasma concentration of low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, triglycerides, apolipoprotein A1, and Apolipoprotein B among 6382 white women in genome-wide analysis with replication.


[PMID 20031577OA-icon.png] Novel loci, including those related to Crohn disease, psoriasis, and inflammation, identified in a genome-wide association study of fibrinogen in 17 686 women: the Women's Genome Health Study.


[PMID 21647738OA-icon.png] Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.


[PMID 22234866OA-icon.png] Evidence from case-control and longitudinal studies supports associations of genetic variation in APOE, CETP, and IL6 with human longevity.

GWAS snp
PMID [PMID 23562540OA-icon.png]
Trait Alzheimer's disease biomarkers
Title GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Risk Allele A
P-val 2E-16
Odds Ratio .08 [NR] unit increase


[PMID 24468470] Genetic susceptibility to accelerated cognitive decline in the US Health and Retirement Study


[PMID 28800603OA-icon.png] Genetic variants specific to aging-related verbal memory: Insights from GWASs in a population-based cohort.


[PMID 32913026OA-icon.png] Association of common genetic variants with brain microbleeds: A Genome-wide Association Study.