rs748404
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (C;C) | 0 | |
| (C;T) | 1.15 | very slightly increased risk (1.15) for lung cancer |
| (T;T) | 1.25 | slightly increased risk (1.25) for lung cancer |
| Reference | GRCh38 38.1/141 |
| Chromosome | 15 |
| Position | 43267033 |
| Gene | TGM5 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs748404 |
| dbSNP (classic) | rs748404 |
| ClinGen | rs748404 |
| ebi | rs748404 |
| HLI | rs748404 |
| Exac | rs748404 |
| Gnomad | rs748404 |
| Varsome | rs748404 |
| LitVar | rs748404 |
| Map | rs748404 |
| PheGenI | rs748404 |
| Biobank | rs748404 |
| 1000 genomes | rs748404 |
| hgdp | rs748404 |
| ensembl | rs748404 |
| geneview | rs748404 |
| scholar | rs748404 |
| rs748404 | |
| pharmgkb | rs748404 |
| gwascentral | rs748404 |
| openSNP | rs748404 |
| 23andMe | rs748404 |
| SNPshot | rs748404 |
| SNPdbe | rs748404 |
| MSV3d | rs748404 |
| GWAS Ctlg | rs748404 |
| GMAF | 0.1524 |
| Max Magnitude | 1.25 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
In a GWAS dataset of 1,447 lung cancer cases, and then replicated in another 1300 cases, the rs748404(T) allele was significantly correlated with increased risk (odds ratio 1.15, p = 1.1 × 10e-9), in agreement with a previous meta-analysis.[PMID 21303977
]
[PMID 19654303] Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study
