rs732609

plus

Geno	Mag	Summary
(A;A)	0	common in clinvar

Make rs732609(A;C)

Make rs732609(C;C)

Reference

GRCh38 38.1/141

Chromosome

2

Position

1496155

Gene

TPO

is a	snp
is	mentioned by
dbSNP	rs732609
dbSNP (classic)	rs732609
ClinGen	rs732609
ebi	rs732609
HLI	rs732609
Exac	rs732609
Gnomad	rs732609
Varsome	rs732609
LitVar	rs732609
Map	rs732609
PheGenI	rs732609
Biobank	rs732609
1000 genomes	rs732609
hgdp	rs732609
ensembl	rs732609
geneview	rs732609
scholar	rs732609
google	rs732609
pharmgkb	rs732609
gwascentral	rs732609
openSNP	rs732609
23andMe	rs732609
SNPshot	rs732609
SNPdbe	rs732609
MSV3d	rs732609
GWAS Ctlg	rs732609

GMAF

0.4706

Max Magnitude

0

?

(A;A) (A;C) (C;C)

28

[PMID 23754668] TPO genetic variants and risk of differentiated thyroid carcinoma in two European populations. This article gave complex data. The heterozygous polymorphism (AC) gave 0.87x lower risk of hypothyroidism among Italians, but 2x increased risk among Spanish. Thyroid cancer risk 0.93 among Italians, 1.7 among Spanish.

[PMID 24420335] Genetic analysis of thyroid peroxidase (TPO) gene in patients whose hypothyroidism was found in adulthood in West Bengal, India

ClinVar
Risk	rs732609(C;C) rs732609(G;G)
Alt	rs732609(C;C) rs732609(G;G)
Reference	Rs732609(A;A)
Significance	Probable-non-pathogenic
Disease	not specified Congenital hypothyroidism
Variation	info
Gene	TPO
CLNDBN	not specified Congenital hypothyroidism
Reversed	0
HGVS	NC_000002.11:g.1499927A>C
CLNSRC
CLNACC	RCV000251285.1, RCV000334090.1,