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rs7190458

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2.1 Higher pancreatic cancer risk
(A;G) 2 Slightly higher pancreatic cancer risk
(G;G) 0 common genotype
ReferenceGRCh38 38.1/141
Chromosome16
Position75229763
GeneBCAR1
is asnp
is mentioned by
dbSNPrs7190458
dbSNP (classic)rs7190458
ClinGenrs7190458
ebirs7190458
HLIrs7190458
Exacrs7190458
Gnomadrs7190458
Varsomers7190458
LitVarrs7190458
Maprs7190458
PheGenIrs7190458
Biobankrs7190458
1000 genomesrs7190458
hgdprs7190458
ensemblrs7190458
geneviewrs7190458
scholarrs7190458
googlers7190458
pharmgkbrs7190458
gwascentralrs7190458
openSNPrs7190458
23andMers7190458
SNPshotrs7190458
SNPdbers7190458
MSV3drs7190458
GWAS Ctlgrs7190458
Max Magnitude2.1
? (A;A) (A;G) (G;G) 28


A 2014 study "Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer" of 7,683 European cases and 14,397 controls found the minor allele rs7190458(A) in BCAR1 (breast cancer anti-estrogen resistance 1) conferring risk of statistically genome-wide significance (per-allele odds ratio (OR) = 1.46, 95% confidence interval (CI) 1.30-1.65, P = 1.1E-10) for Pancreatic cancer.


[PMID 25086665OA-icon.png] Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer