rs7190458
From SNPedia
Orientation | plus |
Stabilized | plus |
Geno | Mag | Summary |
---|---|---|
(A;A) | 2.1 | Higher pancreatic cancer risk |
(A;G) | 2 | Slightly higher pancreatic cancer risk |
(G;G) | 0 | common genotype |
Reference | GRCh38 38.1/141 |
Chromosome | 16 |
Position | 75229763 |
Gene | BCAR1 |
is a | snp |
is | mentioned by |
dbSNP | rs7190458 |
dbSNP (classic) | rs7190458 |
ClinGen | rs7190458 |
ebi | rs7190458 |
HLI | rs7190458 |
Exac | rs7190458 |
Gnomad | rs7190458 |
Varsome | rs7190458 |
LitVar | rs7190458 |
Map | rs7190458 |
PheGenI | rs7190458 |
Biobank | rs7190458 |
1000 genomes | rs7190458 |
hgdp | rs7190458 |
ensembl | rs7190458 |
geneview | rs7190458 |
scholar | rs7190458 |
rs7190458 | |
pharmgkb | rs7190458 |
gwascentral | rs7190458 |
openSNP | rs7190458 |
23andMe | rs7190458 |
SNPshot | rs7190458 |
SNPdbe | rs7190458 |
MSV3d | rs7190458 |
GWAS Ctlg | rs7190458 |
Max Magnitude | 2.1 |
? | (A;A) (A;G) (G;G) | 28 |
---|---|---|
|
A 2014 study "Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer" of 7,683 European cases and 14,397 controls found the minor allele rs7190458(A) in BCAR1 (breast cancer anti-estrogen resistance 1) conferring risk of statistically genome-wide significance (per-allele odds ratio (OR) = 1.46, 95% confidence interval (CI) 1.30-1.65, P = 1.1E-10) for Pancreatic cancer.
[PMID 25086665] Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer