| GWAS snp
|
| PMID
|
[PMID 20719862]
|
| Trait
|
|
| Title
|
New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8
|
| Risk Allele
|
A
|
| P-val
|
5E-8
|
| Odds Ratio
|
0.13 [0.09-0.18] unit decrease
|
[PMID 21098505] Collagen related genes influence glaucoma risk factor, central corneal thickness
[PMID 20485516
] Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.
| GWAS snp
|
| PMID
|
[PMID 23291589]
|
| Trait
|
Corneal structure
|
| Title
|
Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.
|
| Risk Allele
|
T
|
| P-val
|
5E-12
|
| Odds Ratio
|
.13 [0.091-0.169] unit decrease
|
[PMID 23513063] Genetic association of COL5A1 variants in keratoconus patients suggests a complex connection between corneal thinning and keratoconus.
[PMID 25675348] Evaluating the Association between Keratoconus and Reported Genetic Loci in a Han Chinese Population
] Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.
