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rs667282

From SNPedia

Orientationplus
Stabilizedplus
Make rs667282(C;C)
Make rs667282(C;T)
Make rs667282(T;T)
ReferenceGRCh38 38.1/141
Chromosome15
Position78571130
GeneCHRNA5
is asnp
is mentioned by
dbSNPrs667282
dbSNP (classic)rs667282
ClinGenrs667282
ebirs667282
HLIrs667282
Exacrs667282
Gnomadrs667282
Varsomers667282
LitVarrs667282
Maprs667282
PheGenIrs667282
Biobankrs667282
1000 genomesrs667282
hgdprs667282
ensemblrs667282
geneviewrs667282
scholarrs667282
googlers667282
pharmgkbrs667282
gwascentralrs667282
openSNPrs667282
23andMers667282
SNPshotrs667282
SNPdbers667282
MSV3drs667282
GWAS Ctlgrs667282
GMAF0.3655
Max Magnitude0
? (C;C) (C;T) (T;T) 28


[PMID 19491260] Genetic Variants on Chromosome 15q25 Associated with Lung Cancer Risk in Chinese Populations


[PMID 18519524OA-icon.png] Variants in nicotinic receptors and risk for nicotine dependence.


[PMID 19330903OA-icon.png] Gene by smoking interaction in hypertension: identification of a major quantitative trait locus on chromosome 15q for systolic blood pressure in Mexican-Americans.


[PMID 19443489OA-icon.png] Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.


[PMID 19706762OA-icon.png] The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.

GWAS snp
PMID [PMID 22832964OA-icon.png]
Trait
Title Genome-wide meta-analyses of smoking behaviors in African Americans.
Risk Allele C
P-val 2E-7
Odds Ratio 0.0330 None


[PMID 23844051OA-icon.png] Association of CHRNA5-A3-B4 Variation with Esophageal Squamous Cell Carcinoma Risk and Smoking Behaviors in a Chinese Population


[PMID 23576140] Is susceptibility locus for lung cancer in the 15q25 nicotinic acetylcholine receptor gene cluster CHRNA5-A3-B4 associated with risk of gastric cancer?


[PMID 31942417OA-icon.png] Chronic Obstructive Pulmonary Disease Risk and Smoking Cessation Changes Induced by CHRNA5-A3 and CHRNB3-A6 Variation in a Chinese Male Population.