rs6435862

increases the odds of aggressive neuroblastoma

plus

Geno	Mag	Summary
(G;G)	2	2.8x higher risk of aggressive neuroblastoma
(G;T)	1.5	1.7x higher risk of aggressive neuroblastoma
(T;T)	0	Normal risk of aggressive neuroblastoma.

Reference

GRCh38 38.1/141

Chromosome

2

Position

214807822

Gene

BARD1

is a	snp
is	mentioned by
dbSNP	rs6435862
dbSNP (classic)	rs6435862
ClinGen	rs6435862
ebi	rs6435862
HLI	rs6435862
Exac	rs6435862
Gnomad	rs6435862
Varsome	rs6435862
LitVar	rs6435862
Map	rs6435862
PheGenI	rs6435862
Biobank	rs6435862
1000 genomes	rs6435862
hgdp	rs6435862
ensembl	rs6435862
geneview	rs6435862
scholar	rs6435862
google	rs6435862
pharmgkb	rs6435862
gwascentral	rs6435862
openSNP	rs6435862
23andMe	rs6435862
SNPshot	rs6435862
SNPdbe	rs6435862
MSV3d	rs6435862
GWAS Ctlg	rs6435862

GMAF

0.2075

Max Magnitude

2

?

(G;G) (G;T) (T;T)

28

[PMID 19412175 ] Common variations in BARD1 influence susceptibility to high-risk neuroblastoma

Each G allele has been associated with an allelic odds ratio of 1.68 (p = 8.65 x 10(-18)) for risk of aggressive neuroblastoma.

OMIM	256700
Desc	NEUROBLASTOMA
Variant
Related	also

OMIM	613016
Desc
Variant
Related	also

[PMID 23222812 ] Replication of GWAS-identified neuroblastoma risk loci strengthens the role of BARD1 and affirms the cumulative effect of genetic variations on disease susceptibility

[PMID 31258718 ] Functional Polymorphisms in BARD1 Association with Neuroblastoma in a regional Han Chinese Population.