rs6141

Orientation

minus

Stabilized

minus

Geno	Mag	Summary
(G;G)	0	common in clinvar

Make rs6141(A;A)

Make rs6141(A;G)

Reference

GRCh38 38.1/141

Chromosome

3

Position

184372478

Gene

THPO

is a	snp
is	mentioned by
dbSNP	rs6141
dbSNP (classic)	rs6141
ClinGen	rs6141
ebi	rs6141
HLI	rs6141
Exac	rs6141
Gnomad	rs6141
Varsome	rs6141
LitVar	rs6141
Map	rs6141
PheGenI	rs6141
Biobank	rs6141
1000 genomes	rs6141
hgdp	rs6141
ensembl	rs6141
geneview	rs6141
scholar	rs6141
google	rs6141
pharmgkb	rs6141
gwascentral	rs6141
openSNP	rs6141
23andMe	rs6141
SNPshot	rs6141
SNPdbe	rs6141
MSV3d	rs6141
GWAS Ctlg	rs6141

GMAF

0.3797

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

GWAS snp
PMID	[PMID 22139419]
Trait	Platelet counts
Title	New gene functions in megakaryopoiesis and platelet formation.
Risk Allele	T
P-val	6E-8
Odds Ratio	2.47 [1.57-3.36] 10^9/l increase

[PMID 20808897] Disease-associated mutations that alter the RNA structural ensemble.

GWAS snp
PMID	[PMID 20139978]
Trait	Platelet counts
Title	Genome-wide association study of hematological and biochemical traits in a Japanese population.
Risk Allele	T
P-val	5E-11
Odds Ratio	.08 [0.052-0.100] unit increase

[PMID 27401010] Association of BAK1 single nucleotide polymorphism with a risk for dengue hemorrhagic fever.

ClinVar
Risk	rs6141(A;A) rs6141(C;C)
Alt	rs6141(A;A) rs6141(C;C)
Reference	Rs6141(G;G)
Significance	Non-pathogenic
Disease	Essential thrombocythemia
Variation	info
Gene	THPO
CLNDBN	Essential thrombocythemia
Reversed	1
HGVS	NC_000003.11:g.184090266C>T
CLNSRC
CLNACC	RCV000295508.1,