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rs5743815

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(T;T) 0 common in complete genomics
Make rs5743815(C;C)
Make rs5743815(C;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position38828194
GeneTLR6
is asnp
is mentioned by
dbSNPrs5743815
dbSNP (classic)rs5743815
ClinGenrs5743815
ebirs5743815
HLIrs5743815
Exacrs5743815
Gnomadrs5743815
Varsomers5743815
LitVarrs5743815
Maprs5743815
PheGenIrs5743815
Biobankrs5743815
1000 genomesrs5743815
hgdprs5743815
ensemblrs5743815
geneviewrs5743815
scholarrs5743815
googlers5743815
pharmgkbrs5743815
gwascentralrs5743815
openSNPrs5743815
23andMers5743815
SNPshotrs5743815
SNPdbers5743815
MSV3drs5743815
GWAS Ctlgrs5743815
GMAF0.01561
Max Magnitude0
? (C;C) (C;T) (T;T) 28


rs5743815, a SNP in the TLR6 gene also known as V427A, is associated with risk for developing Non-Hodgkin Lymphoma based on a study of 458 patients. The odds ratio is 5.20 (CI: 1.77-15.3, p<0.01). [PMID 17827388OA-icon.png]


[PMID 19505919OA-icon.png] Toll-like receptor signaling pathway variants and prostate cancer mortality.


[PMID 19543401OA-icon.png] Toll-like receptor polymorphisms and susceptibility to urinary tract infections in adult women.


[PMID 19567509OA-icon.png] Genetic variants and prostate cancer risk: candidate replication and exploration of viral restriction genes.


[PMID 20200442OA-icon.png] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.


[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.