rs5743551
| Orientation | minus |
| Stabilized | minus |
| Make rs5743551(A;A) |
| Make rs5743551(A;G) |
| Make rs5743551(G;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 4 |
| Position | 38806033 |
| Gene | TLR1 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs5743551 |
| dbSNP (classic) | rs5743551 |
| ClinGen | rs5743551 |
| ebi | rs5743551 |
| HLI | rs5743551 |
| Exac | rs5743551 |
| Gnomad | rs5743551 |
| Varsome | rs5743551 |
| LitVar | rs5743551 |
| Map | rs5743551 |
| PheGenI | rs5743551 |
| Biobank | rs5743551 |
| 1000 genomes | rs5743551 |
| hgdp | rs5743551 |
| ensembl | rs5743551 |
| geneview | rs5743551 |
| scholar | rs5743551 |
| rs5743551 | |
| pharmgkb | rs5743551 |
| gwascentral | rs5743551 |
| openSNP | rs5743551 |
| 23andMe | rs5743551 |
| SNPshot | rs5743551 |
| SNPdbe | rs5743551 |
| MSV3d | rs5743551 |
| GWAS Ctlg | rs5743551 |
| GMAF | 0.4651 |
| Max Magnitude | 0 |
[PMID 18635889
] excessive inflammation during an infection and contribute to an increased risk for poor outcomes in patients with sepsis
G allele of TLR1-7202A/G (rs5743551)
associations with death, organ dysfunction
associated with elevated TLR1-mediated cytokine production (P < 2x10(-20))
predicted worse organ dysfunction and death (OR 1.82, 95% CI 1.07-3.09).
sepsis-related ALI (OR 3.40, 95% CI 1.59-7.27)
and gram-positive infection in sepsis.
[PMID 18396467] Genetic variation and haplotype structures of innate immunity genes in eastern India.
[PMID 18752252] Genetic variation in the toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk.
[PMID 18768484] Family-based samples can play an important role in genetic association studies.
[PMID 19505919] Toll-like receptor signaling pathway variants and prostate cancer mortality.
[PMID 20200442] Sequence variants in the TLR4 and TLR6-1-10 genes and prostate cancer risk. Results based on pooled analysis from three independent studies.
[PMID 21274447] Genetic polymorphisms and posttraumatic complications.
[PMID 21872627] Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
[PMID 23478521] Toll-Like Receptor 1 Polymorphisms and Associated Outcomes in Sepsis After Traumatic Injury: A Candidate Gene Association Study
[PMID 25128583] Association of TLR and TREM-1 Gene Polymorphisms with Risk of Coronary Artery Disease in a Russian Population
[PMID 25213166] An association between single nucleotide polymorphisms within TLR and TREM-1 genes and infective endocarditis
