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rs4565946

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) Risk of early-onset OCD
(C;T)
(T;T) None
ReferenceGRCh38 38.1/141
Chromosome12
Position71942989
GeneTPH2
is asnp
is mentioned by
dbSNPrs4565946
dbSNP (classic)rs4565946
ClinGenrs4565946
ebirs4565946
HLIrs4565946
Exacrs4565946
Gnomadrs4565946
Varsomers4565946
LitVarrs4565946
Maprs4565946
PheGenIrs4565946
Biobankrs4565946
1000 genomesrs4565946
hgdprs4565946
ensemblrs4565946
geneviewrs4565946
scholarrs4565946
googlers4565946
pharmgkbrs4565946
gwascentralrs4565946
openSNPrs4565946
23andMers4565946
SNPshotrs4565946
SNPdbers4565946
MSV3drs4565946
GWAS Ctlgrs4565946
GMAF0.2998
Max Magnitude0
? (C;C) (C;T) (T;T) 28


[PMID 16146581] rs4570625 and rs4565946 linked to the pathogenesis of early-onset obsessive compulsive disorder


[PMID 19800079] Association of polymorphisms of the tryptophan hydroxylase 2 gene with risk for bipolar disorder or suicidal behavior


[PMID 16116490] Transmission disequilibrium of polymorphic variants in the tryptophan hydroxylase-2 gene in attention-deficit/hyperactivity disorder.


[PMID 17346350OA-icon.png] Case-control and family-based association studies of candidate genes in autistic disorder and its endophenotypes: TPH2 and GLO1.


[PMID 20403506OA-icon.png] Genetic variation in neuroendocrine genes associates with somatic symptoms in the general population: results from the EPIFUND study.


[PMID 21085052] Association study of tryptophan hydroxylase 2 gene polymorphisms in bipolar disorder patients with panic disorder comorbidity.


[PMID 21412658] Associations between polymorphic variants of the tryptophan hydroxylase 2 gene and obsessive-compulsive disorder.


[PMID 21873838] Association between tryptophan hydroxylase-2 gene and late-onset depression.

Tourette's Syndrome


[PMID 24458851] Tryptophan hydroxylase 2 gene polymorphisms in Japanese patients with medication overuse headaches


[PMID 22655589] Investigation of tryptophan hydroxylase 2 (TPH2) in schizophrenia and in the response to antipsychotics.


[PMID 22835848] Tryptophan hydroxylase 2 gene polymorphisms and poststroke anxiety disorders.