rs4253623

plus

Geno	Mag	Summary
(A;A)	0	normal
(A;G)		1.25x higher risk of nonfatal myocardial infarction
(G;G)		1.25x higher risk of nonfatal myocardial infarction

Reference

GRCh38 38.1/141

Chromosome

22

Position

46154203

Gene

PPARA

is a	snp
is	mentioned by
dbSNP	rs4253623
dbSNP (classic)	rs4253623
ClinGen	rs4253623
ebi	rs4253623
HLI	rs4253623
Exac	rs4253623
Gnomad	rs4253623
Varsome	rs4253623
LitVar	rs4253623
Map	rs4253623
PheGenI	rs4253623
Biobank	rs4253623
1000 genomes	rs4253623
hgdp	rs4253623
ensembl	rs4253623
geneview	rs4253623
scholar	rs4253623
google	rs4253623
pharmgkb	rs4253623
gwascentral	rs4253623
openSNP	rs4253623
23andMe	rs4253623
SNPshot	rs4253623
SNPdbe	rs4253623
MSV3d	rs4253623
GWAS Ctlg	rs4253623

GMAF

0.1097

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

rs4253623(G) alleles are associated with a slightly higher risk of nonfatal myocardial infarction (odds ratio 1.25, CI: 1.08 - 1.46) in 848 patients composed of both postmenopausal women and hypertensive men/women.[PMID 18549840 ]

[PMID 18586686 ] Peroxisome proliferator-activated receptor-alpha (PPARA) genetic polymorphisms and breast cancer risk: a Long Island ancillary study.

[PMID 20426853 ] Association and interaction of PPAR-complex gene variants with latent traits of left ventricular diastolic function.

[PMID 31833563] A novel multi-locus genetic risk score identifies patients with higher risk of generalized aggressive periodontitis.