| GWAS snp
|
| PMID
|
[PMID 19060906 ]
|
| Trait
|
LDL cholesterol
|
| Title
|
Common variants at 30 loci contribute to polygenic dyslipidemia
|
| Risk Allele
|
T
|
| P-val
|
8E-12
|
| Odds Ratio
|
0.07 [0.03-0.11] SD increase
|
LDL cholesterol levels being the quantitative trait associated with in [PMID 19197348]
| GWAS snp
|
| PMID
|
[PMID 19197348]
|
| Trait
|
Quantitative traits
|
| Title
|
Genome-wide association studies in an isolated founder population from the Pacific Island of Kosrae
|
| Risk Allele
|
T
|
| P-val
|
0.000001
|
| Odds Ratio
|
0.21 [NR] mg/dL increase
|
[PMID 18802019] Common SNPs in HMGCR in micronesians and whites associated with LDL-cholesterol levels affect alternative splicing of exon13.
[PMID 19554360] The HMG-CoA reductase gene and lipid and lipoprotein levels: the multi-ethnic study of atherosclerosis.
[PMID 19951432] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
[PMID 20005478] The role of HMGCR alternative splicing in statin efficacy.
]
