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rs3842

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0
Make rs3842(A;G)
Make rs3842(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position87504050
GeneABCB1
is asnp
is mentioned by
dbSNPrs3842
dbSNP (classic)rs3842
ClinGenrs3842
ebirs3842
HLIrs3842
Exacrs3842
Gnomadrs3842
Varsomers3842
LitVarrs3842
Maprs3842
PheGenIrs3842
Biobankrs3842
1000 genomesrs3842
hgdprs3842
ensemblrs3842
geneviewrs3842
scholarrs3842
googlers3842
pharmgkbrs3842
gwascentralrs3842
openSNPrs3842
23andMers3842
SNPshotrs3842
SNPdbers3842
MSV3drs3842
GWAS Ctlgrs3842
GMAF0.2006
Max Magnitude0
? (A;A) (A;G) (G;G) 28


[PMID 19107762] rs3842 (A;G) and (G;G) was associated with increased risk of developing lung cancer (odds ratio [OR]. 1.36; 95% confidence interval [95% CI], 1.06-1.76), especially in women (2.5x)

rs212090(A;T) (T;T) increased cancer susceptibility (OR, 1.37; 95% CI, 1.03-1.83)


[PMID 17267408OA-icon.png] Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells.


[PMID 19844206OA-icon.png] Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.


[PMID 19916993OA-icon.png] A novel polymorphism in ABCB1 gene, CYP2B6*6 and sex predict single-dose efavirenz population pharmacokinetics in Ugandans.


[PMID 23133441OA-icon.png] ABCB1 4036A>G and 1236C>T Polymorphisms Affect Plasma Efavirenz Levels in South African HIV/AIDS Patients.


[PMID 23996099] ABCB1 and ABCC1 variants associated with virological failure of first-line protease inhibitors antiretroviral regimens in Northeast Brazil patients