rs3796530

minus

Geno	Mag	Summary
(C;C)	0	common in complete genomics

Make rs3796530(C;T)

Make rs3796530(T;T)

Reference

GRCh38 38.1/141

Chromosome

4

Position

56931087

Gene

REST

is a	snp
is	mentioned by
dbSNP	rs3796530
dbSNP (classic)	rs3796530
ClinGen	rs3796530
ebi	rs3796530
HLI	rs3796530
Exac	rs3796530
Gnomad	rs3796530
Varsome	rs3796530
LitVar	rs3796530
Map	rs3796530
PheGenI	rs3796530
Biobank	rs3796530
1000 genomes	rs3796530
hgdp	rs3796530
ensembl	rs3796530
geneview	rs3796530
scholar	rs3796530
google	rs3796530
pharmgkb	rs3796530
gwascentral	rs3796530
openSNP	rs3796530
23andMe	rs3796530
SNPshot	rs3796530
SNPdbe	rs3796530
MSV3d	rs3796530
GWAS Ctlg	rs3796530

GMAF

0.06612

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

[PMID 18518926] - rs2227902 and rs3796530 were found to be in 100% LD with a VNTR length variant in the REST gene in a sample of 746 elderly Caucasians. Minor alleles (T and A, respectively) at both locations associated with the 4-length VNTR, while common alleles associated with the VNTR 5-length repeat. Carriers of the 4-length VNTR homozygous for the Val66 variant in the BDNF gene performed slightly, but significantly (p = 0.004), better than those without in the general cognitive tests performed in the study. Carriers of the 5-length VNTR and the 66Met BDNF variant had significantly lower g (p = 0.01), but the effect was not as great as the individual effect of the 66Met allele.