rs3761218
From SNPedia
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;G) | 0 | |
| (C;C) | 1.3x risk | |
| (C;T) | 0 | normal |
| (G;G) | 0 | |
| (T;T) | normal |
| Reference | GRCh38 38.1/141 |
| Chromosome | 20 |
| Position | 3795528 |
| Gene | CDC25B |
| is a | snp |
| is | mentioned by |
| dbSNP | rs3761218 |
| dbSNP (classic) | rs3761218 |
| ClinGen | rs3761218 |
| ebi | rs3761218 |
| HLI | rs3761218 |
| Exac | rs3761218 |
| Gnomad | rs3761218 |
| Varsome | rs3761218 |
| LitVar | rs3761218 |
| Map | rs3761218 |
| PheGenI | rs3761218 |
| Biobank | rs3761218 |
| 1000 genomes | rs3761218 |
| hgdp | rs3761218 |
| ensembl | rs3761218 |
| geneview | rs3761218 |
| scholar | rs3761218 |
| rs3761218 | |
| pharmgkb | rs3761218 |
| gwascentral | rs3761218 |
| openSNP | rs3761218 |
| 23andMe | rs3761218 |
| SNPshot | rs3761218 |
| SNPdbe | rs3761218 |
| MSV3d | rs3761218 |
| GWAS Ctlg | rs3761218 |
| GMAF | 0.337 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
rs3761218 has been reported in a large study to be associated with bipolar disorder.
The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 0.97 (CI 0.81-1.15), and for homozygotes, 1.31 (CI 1.09-1.57). [PMID 17554300
]
| GWAS | |
|---|---|
| SNP | rs3761218 |
| PubMedID | [PMID 17554300]
|
| Condition | Bipolar disorder |
| Gene | NR |
| Risk Allele | C |
| pValue | 7.00E-006 |
| OR | 1.03 |
| 95% CI | 1.15-1.23 |
| GWAS snp | |
|---|---|
| PMID | [PMID 21254220]
|
| Trait | |
| Title | Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder. |
| Risk Allele | |
| P-val | 0.000001 |
| Odds Ratio | None None |
[PMID 19308021] Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort.
