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rs35753505

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 2
(T;T) 0
Make rs35753505(C;T)
ReferenceGRCh38 38.1/141
Chromosome8
Position31616625
is asnp
is mentioned by
dbSNPrs35753505
dbSNP (classic)rs35753505
ClinGenrs35753505
ebirs35753505
HLIrs35753505
Exacrs35753505
Gnomadrs35753505
Varsomers35753505
LitVarrs35753505
Maprs35753505
PheGenIrs35753505
Biobankrs35753505
1000 genomesrs35753505
hgdprs35753505
ensemblrs35753505
geneviewrs35753505
scholarrs35753505
googlers35753505
pharmgkbrs35753505
gwascentralrs35753505
openSNPrs35753505
23andMers35753505
SNPshotrs35753505
SNPdbers35753505
MSV3drs35753505
GWAS Ctlgrs35753505
GMAF0.3457
Max Magnitude2

Rs35753505 (SNP8NRG221533) is located within the 5'-flanking region of the NRG1 (Neuregulin 1) gene.

g2b2mh blog rs35753505(C;C) correlates with frontal brain having to working harder during a working memory task.

[PMID 18455369] personality traits - C allele carriers associated with higher (NEO-FFI) scores of neuroticism and lower scores of conscientiousness in a sample of 523 healthy individuals

[PMID 20036336] The results suggest that subjects with risk alleles show hyperactivations in areas associated with elaborate episodic memory encoding and retrieval strategies.


[PMID 19339916] An association study of the neuregulin 1 gene, bipolar affective disorder and psychosis

[PMID 19856012OA-icon.png] Gene expression of NMDA receptor subunits in the cerebellum of elderly patients with schizophrenia


[PMID 20182055] No association between neuregulin 1 and psychotic symptoms in Alzheimer's disease patients


[PMID 18606232] Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with differences in frontal brain activation in a working memory task in healthy individuals.


[PMID 19350564OA-icon.png] Genetic variation in the schizophrenia-risk gene neuregulin 1 correlates with brain activation and impaired speech production in a verbal fluency task in healthy individuals.


[PMID 19448847OA-icon.png] Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls.


[PMID 19911060OA-icon.png] Persistence criteria for susceptibility genes for schizophrenia: a discussion from an evolutionary viewpoint.


[PMID 22424243] Gene expression of glutamate transporters SLC1A1, SLC1A3 and SLC1A6 in the cerebellar subregions of elderly schizophrenia patients and effects of antipsychotic treatment.


[PMID 23360725OA-icon.png] Association study of neuregulin-1 gene polymorphisms in a North Indian schizophrenia sample


[PMID 25106628] Drugs Targeting SNPrs35753505 of the NRG1 Gene may Prevent the Association of Schizophrenia in a Pakistani Population


[PMID 26071373] Contribution of NRG1 Gene Polymorphisms in Temporal Lobe Epilepsy


[PMID 26534905] Polymorphisms of dopamine pathway genes NRG1 and LMX1A are associated with cognitive performance in bipolar disorder