rs314277

Orientation

plus

Stabilized

plus

Make rs314277(A;A)

Make rs314277(A;C)

Make rs314277(C;C)

Reference

GRCh38 38.1/141

Chromosome

6

Position

104959787

Gene

LIN28B

is a	snp
is	mentioned by
dbSNP	rs314277
dbSNP (classic)	rs314277
ClinGen	rs314277
ebi	rs314277
HLI	rs314277
Exac	rs314277
Gnomad	rs314277
Varsome	rs314277
LitVar	rs314277
Map	rs314277
PheGenI	rs314277
Biobank	rs314277
1000 genomes	rs314277
hgdp	rs314277
ensembl	rs314277
geneview	rs314277
scholar	rs314277
google	rs314277
pharmgkb	rs314277
gwascentral	rs314277
openSNP	rs314277
23andMe	rs314277
SNPshot	rs314277
SNPdbe	rs314277
MSV3d	rs314277
GWAS Ctlg	rs314277

GMAF

0.197

Max Magnitude

0

?

(A;A) (A;C) (C;C)

28

GWAS snp
PMID	[PMID 18391950 ]
Trait	Height
Title	Identification of ten loci associated with height highlights new biological pathways in human growth
Risk Allele	A
P-val	1E-8
Odds Ratio	0.41 [0.26-0.59] cm taller

GWAS snp
PMID	[PMID 19448621 ]
Trait	Menarche and menopause (age at onset)
Title	Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
Risk Allele	A
P-val	3E-13
Odds Ratio	0.16 [0.12-0.20] years older

GWAS snp
PMID	[PMID 20303062 ]
Trait	Digit length ratio
Title	A Variant in LIN28B Is Associated with 2D:4D Finger-Length Ratio, a Putative Retrospective Biomarker of Prenatal Testosterone Exposure
Risk Allele	A
P-val	0.000002
Odds Ratio	0.63 [0.41-0.85] increase in mean 2D:4D

OMIM	136100
Desc	FINGERS, RELATIVE LENGTH OF
Variant
Related	also

OMIM	606255
Desc
Variant
Related	also

OMIM	612882
Desc
Variant
Related	also

[PMID 22822098] Functional Study of Risk Loci of Stem Cell-associated Gene Lin-28B and Associations with Disease Survival Outcomes in Epithelial Ovarian Cancer

[PMID 19030899 ] Genome-wide association scan for stature in Chinese: evidence for ethnic specific loci.

[PMID 19448622] Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche.

[PMID 20398887 ] Distinct variants at LIN28B influence growth in height from birth to adulthood.

[PMID 23508249 ] Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study