rs2820037

Orientation

plus

Stabilized

plus

Geno	Mag	Summary
(A;A)	0	normal
(A;T)		1.5x risk of high blood pressure
(T;T)		1.1x risk of high blood pressure

Reference

GRCh38 38.1/141

Chromosome

1

Position

239273242

is a	snp
is	mentioned by
dbSNP	rs2820037
dbSNP (classic)	rs2820037
ClinGen	rs2820037
ebi	rs2820037
HLI	rs2820037
Exac	rs2820037
Gnomad	rs2820037
Varsome	rs2820037
LitVar	rs2820037
Map	rs2820037
PheGenI	rs2820037
Biobank	rs2820037
1000 genomes	rs2820037
hgdp	rs2820037
ensembl	rs2820037
geneview	rs2820037
scholar	rs2820037
google	rs2820037
pharmgkb	rs2820037
gwascentral	rs2820037
openSNP	rs2820037
23andMe	rs2820037
SNPshot	rs2820037
SNPdbe	rs2820037
MSV3d	rs2820037
GWAS Ctlg	rs2820037

GMAF

0.1809

Max Magnitude

0

?	(A;A) (A;T) (T;T)	28

rs2820037 has been reported in a large study to be associated with high blood pressure.

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with heterozygotes is 1.54 (CI 1.03-2.31), and for homozygotes, 1.09 (CI 0.74-1.62). [PMID 17554300]

GWAS
SNP	rs2820037
PubMedID	[PMID 17554300]
Condition	Hypertension
Gene	RYR2,CHRM3,ZP4
Risk Allele	T
pValue	8.00E-007
OR	1.54
95% CI	1.03-2.31

[PMID 18523456] Replication of the Wellcome Trust genome-wide association study of essential hypertension: the Family Blood Pressure Program.

[PMID 20018036] Using a latent growth curve model for an integrative assessment of the effects of genetic and environmental factors on multiple phenotypes.

[PMID 23438931] Relationships between selected gene polymorphisms and blood pressure sensitivity to weight loss in elderly persons with hypertension.