rs2650000
From SNPedia
| Orientation | minus |
| Stabilized | minus |
| Make rs2650000(G;G) |
| Make rs2650000(G;T) |
| Make rs2650000(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 12 |
| Position | 120951159 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs2650000 |
| dbSNP (classic) | rs2650000 |
| ClinGen | rs2650000 |
| ebi | rs2650000 |
| HLI | rs2650000 |
| Exac | rs2650000 |
| Gnomad | rs2650000 |
| Varsome | rs2650000 |
| LitVar | rs2650000 |
| Map | rs2650000 |
| PheGenI | rs2650000 |
| Biobank | rs2650000 |
| 1000 genomes | rs2650000 |
| hgdp | rs2650000 |
| ensembl | rs2650000 |
| geneview | rs2650000 |
| scholar | rs2650000 |
| rs2650000 | |
| pharmgkb | rs2650000 |
| gwascentral | rs2650000 |
| openSNP | rs2650000 |
| 23andMe | rs2650000 |
| SNPshot | rs2650000 |
| SNPdbe | rs2650000 |
| MSV3d | rs2650000 |
| GWAS Ctlg | rs2650000 |
| GMAF | 0.3274 |
| Max Magnitude | 0 |
| ? | (G;G) (G;T) (T;T) | 28 |
|---|---|---|
|
| ||
per the 23andMe blog, the minor allele of this SNP (A) was associated with increased LDL cholesterol
| SNP | Rarer allele | LDL | HDL | TG |
|---|---|---|---|---|
| rs6544713 | T | + | ||
| rs2650000 | A | + | ||
| rs471364 | C | - | ||
| rs1800961 | T | - | ||
| rs7679 | C | - | + | |
| rs2967605 | T | - | ||
| rs2409722 | T | - | ||
| rs10903129 | A | - | - | - |
| rs6756629 | A | - | + | - |
| rs12670798 | C | + | + | + |
| rs7395662 | A | - | + | + |
| rs174570 | T | - | - | + |
| rs2271293 | A | - | + | - |
| rs2624265 | C | + | ||
| rs2167079 | T | + | ||
| rs9891572 | T | + | ||
| rs4844614 | T | + | ||
| rs5031002 | G | + |
| GWAS snp | |
|---|---|
| PMID | [PMID 19060906 ]
|
| Trait | LDL cholesterol |
| Title | Common variants at 30 loci contribute to polygenic dyslipidemia |
| Risk Allele | A |
| P-val | 2E-8 |
| Odds Ratio | 0.07 [0.03-0.11] SD increase |
| GWAS snp | |
|---|---|
| PMID | [PMID 19060910]
|
| Trait | Other metabolic traits |
| Title | Genome-wide association analysis of metabolic traits in a birth cohort from a founder population |
| Risk Allele | A |
| P-val | 3E-11 |
| Odds Ratio | 0.40 [0.25-0.55] mmol/l decrease |
[PMID 18439548] Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 19951432] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
