rs2000999

Orientation

plus

Stabilized

plus

Make rs2000999(A;A)

Make rs2000999(A;G)

Make rs2000999(G;G)

Reference

GRCh38 38.1/141

Chromosome

16

Position

72074194

Gene	HPR, TXNL4B

is a	snp
is	mentioned by
dbSNP	rs2000999
dbSNP (classic)	rs2000999
ClinGen	rs2000999
ebi	rs2000999
HLI	rs2000999
Exac	rs2000999
Gnomad	rs2000999
Varsome	rs2000999
LitVar	rs2000999
Map	rs2000999
PheGenI	rs2000999
Biobank	rs2000999
1000 genomes	rs2000999
hgdp	rs2000999
ensembl	rs2000999
geneview	rs2000999
scholar	rs2000999
google	rs2000999
pharmgkb	rs2000999
gwascentral	rs2000999
openSNP	rs2000999
23andMe	rs2000999
SNPshot	rs2000999
SNPdbe	rs2000999
MSV3d	rs2000999
GWAS Ctlg	rs2000999

GMAF

0.197

Max Magnitude

0

?	(A;A) (A;G) (G;G)	28

GWAS snp
PMID	[PMID 20686565]
Trait
Title	Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele	A
P-val	2E-22
Odds Ratio	2.0000 None

GWAS snp
PMID	[PMID 22403646]
Trait
Title	A genome-wide association study identifies rs2000999 as a strong genetic determinant of circulating haptoglobin levels.
Risk Allele	A
P-val	8E-59
Odds Ratio	0.1380 None

[PMID 22579477] Clinical necessity of partitioning of human plasma haptoglobin reference intervals by recently-discovered rs2000999.

[PMID 20066028] Modeling of environmental effects in genome-wide association studies identifies SLC2A2 and HP as novel loci influencing serum cholesterol levels.

[PMID 22433445] Complexity of a complex trait locus: HP, HPR, haemoglobin and cholesterol.

GWAS snp
PMID	[PMID 24097068]
Trait	Cholesterol, total
Title	Discovery and refinement of loci associated with lipid levels.
Risk Allele	A
P-val	7E-41
Odds Ratio	.06 [NR] unit increase