rs1978237

plus

Geno	Mag	Summary
(C;C)	1.6	>1.59x risk of Type 2 diabetes
(C;G)	1.6	1.59x risk of Type 2 diabetes
(G;G)	1	No increased risk of Type 2 diabetes

Reference

GRCh38 38.1/141

Chromosome

19

Position

5209630

Gene

PTPRS

is a	snp
is	mentioned by
dbSNP	rs1978237
dbSNP (classic)	rs1978237
ClinGen	rs1978237
ebi	rs1978237
HLI	rs1978237
Exac	rs1978237
Gnomad	rs1978237
Varsome	rs1978237
LitVar	rs1978237
Map	rs1978237
PheGenI	rs1978237
Biobank	rs1978237
1000 genomes	rs1978237
hgdp	rs1978237
ensembl	rs1978237
geneview	rs1978237
scholar	rs1978237
google	rs1978237
pharmgkb	rs1978237
gwascentral	rs1978237
openSNP	rs1978237
23andMe	rs1978237
SNPshot	rs1978237
SNPdbe	rs1978237
MSV3d	rs1978237
GWAS Ctlg	rs1978237

GMAF

0.2631

Max Magnitude

1.6

?

(C;C) (C;G) (G;G)

28

[PMID 17893260] rs1143699, rs4807015, and rs1978237 confer an increased risk of developing type-2 diabetes. "SNP rs1143699 was associated with male T2D patients when compared with NGT controls (odds ratio; OR = 1.57; P = 0.029). SNP rs4807015 showed association with T2D patients when compared with NGT controls (OR = 1.32; P = 0.025). Finally, SNP rs1978237 was associated with T2D patients when compared with NGT controls (OR = 1.59; P = 0.002). Logistic regression analysis demonstrated that for SNP rs1143699 in men, C/C homozygosity conveys an increased risk of T2D (OR = 2.19; P = 0.035), while SNP rs4807015 was associated with an increased risk of T2D in both men and women (OR = 1.74; P = 0.029). SNP rs1978237 also demonstrated a risk of T2D in men and women (OR = 1.59; P = 0.026)." (Abstract)

[PMID 20111712 ] Risk of ovarian cancer and inherited variants in relapse-associated genes.