Rs1954787

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is asnp
is mentioned by
dbSNPrs1954787
hapmaprs1954787
hgdprs1954787
ensemblrs1954787
gopubmedrs1954787
scholarrs1954787
googlers1954787
pharmgkbrs1954787
medrefsnprs1954787
23andMers1954787
GeneGRIK4
Chromosome11
Position120168573
GenotypeEffect
rs1954787(C;C)*~10% more likely to respond to citalopram
rs1954787(C;T)normal risk
rs1954787(T;T)~10% less likely to respond to citalopram
Genotypes Magnitude Summary
Rs1954787(C;T) 00
Rs1954787(T;T) 22

rs1954787, located in an intron of the HTR2A gene, was found to be associated with a somewhat increased rate of successful response to treatment of depression with the drug citalopram. [PMID 17671280]

From the abstract of this article:

"The effect size of (this) GRIK4 marker alone was modest, but homozygote carriers of the treatment-response-associated marker alleles of both the GRIK4 and HTR2A (see rs7997012) genes were 23% less likely to experience nonresponse to (citalopram) treatment relative to participants who did not carry any of these marker alleles."

? (C;C) (C;T) (T;T)
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