rs1799941
| Orientation | plus |
| Stabilized | plus |
| Geno | Mag | Summary |
|---|---|---|
| (A;A) | 1.5 | Sex Hormone-Binding Globulin levels are 0.4 standard deviations higher |
| (A;G) | Sex Hormone-Binding Globulin levels are 0.2 standard deviations higher | |
| (G;G) | 0 |
| Reference | GRCh38 38.1/141 |
| Chromosome | 17 |
| Position | 7630105 |
| Gene | SHBG |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1799941 |
| dbSNP (classic) | rs1799941 |
| ClinGen | rs1799941 |
| ebi | rs1799941 |
| HLI | rs1799941 |
| Exac | rs1799941 |
| Gnomad | rs1799941 |
| Varsome | rs1799941 |
| LitVar | rs1799941 |
| Map | rs1799941 |
| PheGenI | rs1799941 |
| Biobank | rs1799941 |
| 1000 genomes | rs1799941 |
| hgdp | rs1799941 |
| ensembl | rs1799941 |
| geneview | rs1799941 |
| scholar | rs1799941 |
| rs1799941 | |
| pharmgkb | rs1799941 |
| gwascentral | rs1799941 |
| openSNP | rs1799941 |
| 23andMe | rs1799941 |
| SNPshot | rs1799941 |
| SNPdbe | rs1799941 |
| MSV3d | rs1799941 |
| GWAS Ctlg | rs1799941 |
| GMAF | 0.124 |
| Max Magnitude | 1.5 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
[PMID 19574343
] Quantitative trait loci predicting circulating sex steroid hormones in men from the NCI-Breast and Prostate Cancer Cohort Consortium (BPC3)
[PMID 19679209] Effects of Polymorphisms of the Sex Hormone-Binding Globulin (SHBG) Gene on Free Estradiol and Bone Mineral Density
[PMID 19933169] Genetic evidence that raised Sex Hormone Binding Globulin (SHBG) levels reduce the risk of type 2 diabetes
[PMID 16926255] SHBG gene promoter polymorphisms in men are associated with serum sex hormone-binding globulin, androgen and androgen metabolite levels, and hip bone mineral density.
[PMID 17411440] Ovarian cancer risk and common variation in the sex hormone-binding globulin gene: a population-based case-control study.
[PMID 18464913] A genome-wide association study identifies protein quantitative trait loci (pQTLs).
[PMID 18628428] Polymorphisms in genes involved in sex hormone metabolism, estrogen plus progestin hormone therapy use, and risk of postmenopausal breast cancer.
[PMID 18980759] Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect.
[PMID 19064566] Identification of common variants in the SHBG gene affecting sex hormone-binding globulin levels and breast cancer risk in postmenopausal women.
[PMID 19091090] Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women.
[PMID 20616999] Usefulness of Mendelian randomization in observational epidemiology.
[PMID 20841609] Relationships of circulating sex hormone-binding globulin with metabolic traits in humans.
[PMID 21252242] Polymorphisms in the SHBG gene influence serum SHBG levels in women with polycystic ovary syndrome.
[PMID 21283750] Studies of the association of Arg72Pro of tumor suppressor protein p53 with type 2 diabetes in a combined analysis of 55,521 Europeans.
[PMID 21429951] Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility.
[PMID 24327369] Single-nucleotide polymorphism, rs1799941 in the sex hormone-binding globulin (SHBG) gene, related to both serum testosterone and SHBG levels and the risk of myocardial infarction, type 2 diabetes, cancer and mortality in men: the Tromsø Study
[PMID 22936694] Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men.
[PMID 23001781] Common variants in the sex hormone-binding globulin gene (SHBG) and polycystic ovary syndrome (PCOS) in Mediterranean women.
[PMID 25647406] SHBG Gene Polymorphism (rs1799941) Associates with Metabolic Syndrome in Children and Adolescents
[PMID 25671407] A Systems Genetics Approach to Dyslipidemia in Children and Adolescents
