rs1256049
| Orientation | minus |
| Stabilized | minus |
| Geno | Mag | Summary |
|---|---|---|
| (G;G) | 0 | common in complete genomics |
| Make rs1256049(A;A) |
| Make rs1256049(A;G) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 14 |
| Position | 64257333 |
| Gene | ESR2 |
| is a | snp |
| is | mentioned by |
| dbSNP | rs1256049 |
| dbSNP (classic) | rs1256049 |
| ClinGen | rs1256049 |
| ebi | rs1256049 |
| HLI | rs1256049 |
| Exac | rs1256049 |
| Gnomad | rs1256049 |
| Varsome | rs1256049 |
| LitVar | rs1256049 |
| Map | rs1256049 |
| PheGenI | rs1256049 |
| Biobank | rs1256049 |
| 1000 genomes | rs1256049 |
| hgdp | rs1256049 |
| ensembl | rs1256049 |
| geneview | rs1256049 |
| scholar | rs1256049 |
| rs1256049 | |
| pharmgkb | rs1256049 |
| gwascentral | rs1256049 |
| openSNP | rs1256049 |
| 23andMe | rs1256049 |
| SNPshot | rs1256049 |
| SNPdbe | rs1256049 |
| MSV3d | rs1256049 |
| GWAS Ctlg | rs1256049 |
| GMAF | 0.1281 |
| Max Magnitude | 0 |
| ? | (A;A) (A;G) (G;G) | 28 |
|---|---|---|
|
| ||
rs1256049 is a SNP in the estrogen receptor 2 gene ESR2.
[PMID 18939943] rs1256049(A) allele carriers have higher mean carotid artery intima-media thickness (CIMT) as well as maximal CIMT, but this result may be limited to the population studied, in this case individuals from the Cardiovascular Risk in Young Finns study.
[PMID 19298602] Isoflavone, polymorphisms in estrogen receptor genes and breast cancer risk in case-control studies in Japanese, Japanese Brazilians and non-Japanese Brazilians.
[PMID 19111408
] Association of estrogen receptor 2 gene polymorphisms with obesity in women (obesity and estrogen receptor 2 gene)
[PMID 19032032] Associations of the estrogen receptors 1 and 2 gene polymorphisms with the metabolic syndrome in women
[PMID 19715484] No Association between Estrogen Receptor Beta (ESR2) Polymorphisms and Uterine Leiomyoma
[PMID 20390341] A systematic review of the relationship between polymorphic sites in the estrogen receptor-beta (ESR2) gene and breast cancer risk
[PMID 20172949] Polymorphisms of estrogen receptors and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China
[PMID 21523342] Association of Rsa polymorphism of the estrogen receptor-? gene with rheumatoid arthritis
[PMID 22511967] Potential Role of Aromatase over Estrogen Receptor Gene Polymorphisms in Migraine Susceptibility: A Case Control Study from North India
[PMID 22678799] [Association between estrogen receptor beta gene polymorphisms in Chinese Uygur patients and intrahepatic cholestasis of pregnancy]
[PMID 22759347] Association of estrogen receptor beta variants and serum levels of estradiol with risk of colorectal cancer: a case control study
[PMID 16083630] [Association between single-nucleotide polymorphisms in estrogen receptor beta gene and risk of prostate cancer].
[PMID 16118344] Polymorphisms in the estrogen receptor beta (ESR2) gene are associated with bone mineral density in Caucasian men and women.
[PMID 17540666] Allelic estrogen receptor 1 (ESR1) gene variants predict the outcome of ovarian stimulation in in vitro fertilization.
[PMID 17916182] CA repeat and RsaI polymorphisms in ERbeta gene are not associated with infertility in Indian men.
[PMID 17935138] Haplotypes of the estrogen receptor beta gene and breast cancer risk.
[PMID 18053221] Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study.
[PMID 18304720] Estrogen receptor beta gene haplotype is associated with pelvic organ prolapse.
[PMID 18487282] Association between ESR2 genetic variants and risk of myocardial infarction.
[PMID 18579753] Vascular actions of estrogens: functional implications.
[PMID 18592033] Sex steroid-related candidate genes in psychiatric disorders.
[PMID 18627768] Pharmacogenetics of hormone replacement therapy for climacteric symptoms.
[PMID 18805939] Functional genetic polymorphisms and female reproductive disorders: part II--endometriosis.
[PMID 18980759] Polymorphisms of estrogen-related genes jointly confer susceptibility to human spermatogenic defect.
[PMID 18992263] Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways.
[PMID 19337586] Do Estrogen Receptor beta Polymorphisms Play A Role in the Pharmacogenetics of Estrogen Signaling?
[PMID 19438492] Estrogen receptor polymorphisms and the risk of endometrial cancer.
[PMID 19555469] A prospective study of androgen levels, hormone-related genes and risk of rheumatoid arthritis.
[PMID 19630952] Sex steroid metabolism polymorphisms and mammographic density in pre- and early perimenopausal women.
[PMID 19927160] Association between ESR1 and ESR2 gene polymorphisms and hyperlipidemia in Chinese Han postmenopausal women.
[PMID 20346360] Genetic risk factors for hepatopulmonary syndrome in patients with advanced liver disease.
[PMID 20655613] Haplotypes of estrogen receptor-beta and risk of non-small cell lung cancer in women.
[PMID 21429951] Quantitative trait analysis suggests polymorphisms of estrogen-related genes regulate human sperm concentrations and motility.
[PMID 21570196] Estrogen receptor gene variants are associated with anxiety disorders in older women.
[PMID 21762042] Oestrogen receptor polymorphisms in female patients with rheumatoid arthritis.
[PMID 21804148] Oestrogen receptor polymorphisms and late-life depression.
[PMID 22228197] Estrogen receptors alpha (rs2234693 and rs9340799), and beta (rs4986938 and rs1256049) genes polymorphism in prostate cancer: Evidence for association with risk and histopathological tumor characteristics in Iranian men.
[PMID 22324545] Are polymorphisms in oestrogen receptors genes associated with lipid levels in response to hormone therapy?
[PMID 22463697] Association of polymorphisms in the estrogen receptor beta (ESR2) with unexplained recurrent spontaneous abortion (URSA) in Chinese population.
[PMID 23352710] The single nucleotide polymorphism (SNP) of the estrogen receptor-β gene, rs1256049, is associated with knee osteoarthritis in Korean population
[PMID 23506158] Estrogen receptor alpha single nucleotide polymorphism as predictor of diabetes type 2 risk in hypogonadal men
[PMID 23686919] Impact of polymorphisms in the oestrogen receptors alpha and beta (ESR1, ESR2) genes on risk of vasculogenic erectile dysfunction
[PMID 23274843] Given breast cancer, is fat better than thin? Impact of the estrogen receptor beta gene polymorphisms
[PMID 24859835] The influence of ESR1 rs9340799 and ESR2 rs1256049 polymorphisms on prostate cancer risk
[PMID 25128001] Polymorphisms in estrogen receptors predict the risk of male infertility: a meta-analysis
[PMID 25973102] Single nucleotide polymorphisms of ERβ and coronary atherosclerotic disease in Chinese Han women
[PMID 32472323] Association of estrogen receptor β polymorphisms with posterior tibial tendon dysfunction.
