rs12487066

plus

Geno	Mag	Summary
(C;C)	0	>1.09x increased risk for multiple sclerosis
(C;T)		1.09x increased risk for multiple sclerosis
(T;T)		common

Reference

GRCh38 38.1/141

Chromosome

3

Position

106193283

Gene	LOC105374027

is a	snp
is	mentioned by
dbSNP	rs12487066
dbSNP (classic)	rs12487066
ClinGen	rs12487066
ebi	rs12487066
HLI	rs12487066
Exac	rs12487066
Gnomad	rs12487066
Varsome	rs12487066
LitVar	rs12487066
Map	rs12487066
PheGenI	rs12487066
Biobank	rs12487066
1000 genomes	rs12487066
hgdp	rs12487066
ensembl	rs12487066
geneview	rs12487066
scholar	rs12487066
google	rs12487066
pharmgkb	rs12487066
gwascentral	rs12487066
openSNP	rs12487066
23andMe	rs12487066
SNPshot	rs12487066
SNPdbe	rs12487066
MSV3d	rs12487066
GWAS Ctlg	rs12487066

GMAF

0.2612

Max Magnitude

0

?

(C;C) (C;T) (T;T)

28

rs12487066 has been reported in a large study to be associated with multiple sclerosis.

The risk allele (oriented to the dbSNP entry) is (T); the odds ratio associated with this allele is 1.09 (CI 1.03-1.16). [PMID 17660530]

[PMID 20007504 ] Comprehensive follow-up of the first genome-wide association study of multiple sclerosis identifies KIF21B and TMEM39A as susceptibility loci.

[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.