| GWAS snp
|
| PMID
|
[PMID 18587394 ]
|
| Trait
|
Crohn's disease
|
| Title
|
Genome-wide assocation defines more than 30 distinct susceptibility loci for Crohn's disease
|
| Risk Allele
|
C
|
| P-val
|
3E-9
|
| Odds Ratio
|
1.12 [NR]
|
[PMID 20109474] Genetic factors in chronic inflammation: single nucleotide polymorphisms in the STAT-JAK pathway, susceptibility to DNA damage and Crohn's disease in a New Zealand population
| GWAS snp
|
| PMID
|
[PMID 21297633]
|
| Trait
|
|
| Title
|
Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47
|
| Risk Allele
|
C
|
| P-val
|
2E-25
|
| Odds Ratio
|
1.1700 [1.12-1.21]
|
[PMID 22205606] JAK2 and STAT3 polymorphisms in a Han Chinese Population with Behcet's disease
[PMID 22269120] Investigation of JAK2, STAT3 and CCR6 polymorphisms and their gene-gene interactions in inflammatory bowel disease
[PMID 18006699] Host genetic variation contributes to phenotypic diversity in myeloproliferative disorders.
[PMID 19068216] Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship.
[PMID 21304977] An investigation of genome-wide studies reported susceptibility loci for ulcerative colitis shows limited replication in north Indians.
[PMID 22065112] The JAK2 variant rs10758669 in Crohn's disease: altering the intestinal barrier as one mechanism of action.
[PMID 21102463] Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci.
[PMID 23611997] JAK1, but not JAK2 and STAT3, confers susceptibility to Vogt-Koyanagi-Harada (VKH) syndrome in a Han Chinese population
[PMID 24385239] JAK2 rs10758669 Polymorphisms and Susceptibility to Ulcerative Colitis and Crohn's Disease: A Meta-analysis
]
