rs1038304

plus

Geno	Mag	Summary
(A;G)	0

Make rs1038304(A;A)

Make rs1038304(G;G)

Reference

GRCh38 38.1/141

Chromosome

6

Position

151612040

Gene	CCDC170, LOC107986528

is a	snp
is	mentioned by
dbSNP	rs1038304
dbSNP (classic)	rs1038304
ClinGen	rs1038304
ebi	rs1038304
HLI	rs1038304
Exac	rs1038304
Gnomad	rs1038304
Varsome	rs1038304
LitVar	rs1038304
Map	rs1038304
PheGenI	rs1038304
Biobank	rs1038304
1000 genomes	rs1038304
hgdp	rs1038304
ensembl	rs1038304
geneview	rs1038304
scholar	rs1038304
google	rs1038304
pharmgkb	rs1038304
gwascentral	rs1038304
openSNP	rs1038304
23andMe	rs1038304
SNPshot	rs1038304
SNPdbe	rs1038304
MSV3d	rs1038304
GWAS Ctlg	rs1038304

GMAF

0.4568

Max Magnitude

0

?

(A;A) (A;G) (G;G)

28

Rs1038304
PubMed	[PMID 18445777]
Affy Probeset	SNP_A-1988119
Affy Orientation	same
On GW 5.0
Alleles A/B	A/G
Ancestral	G
Population	Caucasian
Allele	G
Case Freq.
Control Freq.
Odds Ratio Het
Odds Ratio Hom
Odds Ratio All	-
Disease	Bone mineral density, lower (BMD-L)

rs1038304 increases susceptibility to Bone mineral density variations, lower for carriers of the G allele [PMID 18445777]

GWAS
SNP	rs1038304
PubMedID	[PMID 18445777]
Condition	Bone mineral density (hip)
Gene	ESR1
Risk Allele	G
pValue	5.00E-009
OR	0.08
95% CI	0.06-0.11) SD decreas

GWAS snp
PMID	[PMID 19079262]
Trait	Bone mineral density (hip)
Title	New sequence variants associated with bone mineral density
Risk Allele	G
P-val	4E-10
Odds Ratio	0.08 [0.06-0.11] SD decrease

OMIM	612114
Desc	BONE MINERAL DENSITY QUANTITATIVE TRAIT LOCUS 11; BMND11
Variant
Related	also

[PMID 21528353] Genetic variants of 6q25 and breast cancer susceptibility: a two-stage fine mapping study in a Chinese population

[PMID 21646926] Interactions of osteoporosis candidate genes for age at menarche, age at natural menopause, and maximal height in Han Chinese women

[PMID 19181680 ] Common variants in the region around Osterix are associated with bone mineral density and growth in childhood.

[PMID 20072603 ] Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis.

[PMID 20534768 ] OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.

[PMID 24481879] Association of ESR1 and C6orf97 gene polymorphism with osteoporosis in postmenopausal women