From SNPedia
| ? | (C;C) (C;T) (T;T) | 28 |
|---|
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rs999737 is located near an interesting gene, RAD51L1, which is in a pathway previously implicated in
breast cancer risk. The protein encoded by this gene interacts directly with those of other genes that are involved in DNA repair and in the exchange of material between strands of DNA.
[PMID 19330030] A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).
| PharmGKB | PA164739884 |
| Name | |
| Annotation | GWAS results: A multistage genome-wide association study in Breast Cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). (Initial Sample Size: 1,145 cases, 1,142 controls; Replication Sample Size: 8,625 cases, 9,657 controls); (Region: 14q24.1; Reported Gene(s): RAD51L1; Risk Allele: rs999737-C); (p-value= 0.0000002).This variant is associated with Breast Cancer. |
| Gene | RAD51L1 |
| Featue | |
| Evidence | PubMed ID:19330030; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Breast Neoplasms |
| Curation Level | Non-Curated |
