Rs931127

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is asnp
is mentioned by
dbSNPrs931127
hapmaprs931127
hgdprs931127
ensemblrs931127
gopubmedrs931127
scholarrs931127
googlers931127
pharmgkbrs931127
hgvbaseg2prs931127
medrefsnprs931127
23andMers931127
SNP Nexus

GeneSIPA1
Chromosome11
Orientationplus
Position65161875
GenotypeEffect
rs931127(A;A)2.15x more likely positive lymph node
rs931127(A;G)2.15x more likely positive lymph node
rs931127(G;G)more favorable


Genotypes Magnitude Summary
Rs931127(A;A) 2.12.1 2.15x more likely positive lymph node
Rs931127(A;G)
Rs931127(G;G) 00 more favorable
PMID: 16563182 This SNP in can have implications for prognosis in breast cancer.

It is located 313 base pairs upstream of the 5'-untranslated region of SIPA1 and is considered to be within the promoter region of the gene. SIPA1 germline polymorphisms are associated with aggressive disease behavior(lymph node metastasis) in the cohort examined

? (A;A) (A;G) (G;G)


[PMID 19906411] Polymorphisms in MMP9 and SIPA1 are associated with increased risk of nodal metastases in early-stage cervical cancer

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