Have questions? Visit https://www.reddit.com/r/SNPedia

rs931127

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2.1 2.15x more likely positive lymph node
(A;G)
(G;G) 0 more favorable
ReferenceGRCh38 38.1/141
Chromosome11
Position65637829
GenePCNX3, SIPA1
is asnp
is mentioned by
dbSNPrs931127
dbSNP (classic)rs931127
ClinGenrs931127
ebirs931127
HLIrs931127
Exacrs931127
Gnomadrs931127
Varsomers931127
LitVarrs931127
Maprs931127
PheGenIrs931127
Biobankrs931127
1000 genomesrs931127
hgdprs931127
ensemblrs931127
geneviewrs931127
scholarrs931127
googlers931127
pharmgkbrs931127
gwascentralrs931127
openSNPrs931127
23andMers931127
SNPshotrs931127
SNPdbers931127
MSV3drs931127
GWAS Ctlgrs931127
GMAF0.4564
Max Magnitude2.1
? (A;A) (A;G) (G;G) 28


PMID: 16563182 This SNP in can have implications for prognosis in breast cancer.

It is located 313 base pairs upstream of the 5'-untranslated region of SIPA1 and is considered to be within the promoter region of the gene. SIPA1 germline polymorphisms are associated with aggressive disease behavior(lymph node metastasis) in the cohort examined


[PMID 19906411OA-icon.png] Polymorphisms in MMP9 and SIPA1 are associated with increased risk of nodal metastases in early-stage cervical cancer


[PMID 19089925OA-icon.png] Genetic variation in SIPA1 in relation to breast cancer risk and survival after breast cancer diagnosis.


[PMID 19264455OA-icon.png] Linkage analysis of schizophrenia in African-American families.


[PMID 19765277OA-icon.png] Polymorphisms of the SIPA1 gene and sporadic breast cancer susceptibility.


[PMID 23661532] Sipa1 promoter polymorphism predicts risk and metastasis of lung cancer in Chinese


[PMID 27504716OA-icon.png] Genes Interacting with Occupational Exposures to Low Molecular Weight Agents and Irritants on Adult-Onset Asthma in Three European Studies.