|| Higher Risk Aneurysm
|?|| (A;A) (A;G) (G;G) ||28|
Based on a large study (~6,000 cases and 14,000 controls) of both European and Japanese populations, the rs9298506
(A) allele has been associated with higher risk of aneurysm
, with an odds ratio per allele of 1.28 (CI:1.20-1.38, p=1.0e-06). [PMID 20364137
] Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness.
|| Insufficiently evaluated pathogenic
[PMID 23733552] Genetic risk factors for intracranial aneurysms: a meta-analysis in more than 116,000 individuals.
[PMID 25053769] Evaluation of genetic risk loci for intracranial aneurysms in sporadic arteriovenous malformations of the brain