rs7578597
| Orientation | plus |
| Stabilized | plus |
| Make rs7578597(C;C) |
| Make rs7578597(C;T) |
| Make rs7578597(T;T) |
| Reference | GRCh38 38.1/141 |
| Chromosome | 2 |
| Position | 43505684 |
| Gene | THADA |
| is a | snp |
| is | mentioned by |
| dbSNP | rs7578597 |
| dbSNP (classic) | rs7578597 |
| ClinGen | rs7578597 |
| ebi | rs7578597 |
| HLI | rs7578597 |
| Exac | rs7578597 |
| Gnomad | rs7578597 |
| Varsome | rs7578597 |
| LitVar | rs7578597 |
| Map | rs7578597 |
| PheGenI | rs7578597 |
| Biobank | rs7578597 |
| 1000 genomes | rs7578597 |
| hgdp | rs7578597 |
| ensembl | rs7578597 |
| geneview | rs7578597 |
| scholar | rs7578597 |
| rs7578597 | |
| pharmgkb | rs7578597 |
| gwascentral | rs7578597 |
| openSNP | rs7578597 |
| 23andMe | rs7578597 |
| SNPshot | rs7578597 |
| SNPdbe | rs7578597 |
| MSV3d | rs7578597 |
| GWAS Ctlg | rs7578597 |
| GMAF | 0.1198 |
| Max Magnitude | 0 |
| ? | (C;C) (C;T) (T;T) | 28 |
|---|---|---|
|
| ||
| GWAS | |
|---|---|
| SNP | rs7578597 |
| PubMedID | [PMID 18372903 ]
|
| Condition | Type 2 diabetes |
| Gene | THADA |
| Risk Allele | T |
| pValue | 1.00E-009 |
| OR | 1.15 |
| 95% CI | 1.10-1.20 |
[PMID 19789630] Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study
[PMID 19862325] PPARG, KCNJ11, CDKAL1, CDKN2A-CDKN2B, IDE-KIF11-HHEX, IGF2BP2 and SLC30A8 Are Associated with Type 2 Diabetes in a Chinese Population
[PMID 22052079] Association analysis of 31 common polymorphisms with type 2 diabetes and its related traits in Indian sib pairs
[PMID 18567820] Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
[PMID 18591388] Assessing the combined impact of 18 common genetic variants of modest effect sizes on type 2 diabetes risk.
[PMID 18694974] Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.
[PMID 18714373] Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.
[PMID 18782870] Clinical review: the genetics of type 2 diabetes: a realistic appraisal in 2008.
[PMID 18852197] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.
[PMID 19020323] Genotype score in addition to common risk factors for prediction of type 2 diabetes.
[PMID 19056611] Adiposity-related heterogeneity in patterns of type 2 diabetes susceptibility observed in genome-wide association data.
[PMID 19096518] Novel association of HK1 with glycated hemoglobin in a non-diabetic population: a genome-wide evaluation of 14,618 participants in the Women's Genome Health Study.
[PMID 19207020] Meta-analysis in genome-wide association studies.
[PMID 19323962] Genome-wide association studies in type 2 diabetes.
[PMID 19324937] Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.
[PMID 19341491] Genome-based prediction of common diseases: methodological considerations for future research.
[PMID 19401414] Confirmation of multiple risk Loci and genetic impacts by a genome-wide association study of type 2 diabetes in the Japanese population.
[PMID 19455305] No association of multiple type 2 diabetes loci with type 1 diabetes.
[PMID 19460916] Genetic architecture of type 2 diabetes: recent progress and clinical implications.
[PMID 19474294] Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
[PMID 19502414] Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.
[PMID 19526209] Is the thrifty genotype hypothesis supported by evidence based on confirmed type 2 diabetes- and obesity-susceptibility variants?
[PMID 19602701] Underlying genetic models of inheritance in established type 2 diabetes associations.
[PMID 19670153] Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits.
[PMID 19741467] Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.
[PMID 19956539] How many genetic variants remain to be discovered?
[PMID 20017978] Influence of control selection in genome-wide association studies: the example of diabetes in the Framingham Heart Study.
[PMID 20043853] Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus.
[PMID 20075150] Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.
[PMID 20144327] A genomics study of type 2 diabetes mellitus in U.S. Air Force personnel.
[PMID 20712903] Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.
[PMID 21278902] Genetic risk profiling for prediction of type 2 diabetes.
[PMID 21602532] Type 2 diabetes risk variants and colorectal cancer risk: the Multiethnic Cohort and PAGE studies.
[PMID 22237986] Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.
[PMID 22377712] Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography.
[PMID 23036851] Treatment factors rather than genetic variation determine metabolic syndrome in childhood cancer survivors
[PMID 23462794] Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
[PMID 27155871] Excess maternal transmission of variants in the THADA gene to offspring with type 2 diabetes.
