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Rs7483

From SNPedia

Orientationminus
Stabilizedplus
Make rs7483(A;A)
Make rs7483(A;G)
Make rs7483(G;G)
ReferenceGRCh38 38.1/142
Chromosome1
Position109737079
GeneGSTM3
is asnp
is mentioned by
dbSNPrs7483
ebirs7483
Exacrs7483
PheGenIrs7483
hapmaprs7483
1000 genomesrs7483
hgdprs7483
ensemblrs7483
gopubmedrs7483
geneviewrs7483
scholarrs7483
googlers7483
pharmgkbrs7483
gwascentralrs7483
openSNPrs7483
23andMers7483
23andMe allrs7483
SNP Nexus

SNPshotrs7483
SNPdbers7483
MSV3drs7483
GWAS Ctlgrs7483
GMAF0.3806
Max Magnitude
? (A;A) (A;G) (G;G) 28

[PMID 18423940] association of the rs7483 SNP with late-onset Alzheimer's disease


[PMID 19696791] Association between polymorphisms in glutathione S-transferase Mu3 and IgG titer levels in serum against Helicobacter pylori


[PMID 16112301OA-icon.png] NAT2 slow acetylation, GSTM1 null genotype, and risk of bladder cancer: results from the Spanish Bladder Cancer Study and meta-analyses.


[PMID 17601350OA-icon.png] A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.


[PMID 17904251] Gene variations in GSTM3 are a risk factor for Alzheimer's disease.


[PMID 19151192OA-icon.png] Variation in the GST mu locus and tobacco smoke exposure as determinants of childhood lung function.


[PMID 19223546OA-icon.png] Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer.


[PMID 21799460] HapMap-based study of human soluble glutathione S-transferase enzymes: the role of natural selection in shaping the single nucleotide polymorphism diversity of xenobiotic-metabolizing genes.


[PMID 23036584] Discovery by the Epistasis Project of an epistatic interaction between the GSTM3 gene and the HHEX/IDE/KIF11 locus in the risk of Alzheimer's disease


GET Evidence
GSTM3-V224I
aa_change Val224Ile
aa_change_short V224I
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.232199
summary



[PMID 24157827OA-icon.png] Genetic variation in the GSTM3 promoter confer risk and prognosis of renal cell carcinoma by reducing gene expression