From SNPedia
| ? | (A;A) (A;G) (G;G) | 28 |
|---|
 |
| GWAS snp
|
| PMID
|
[PMID 18823527]
|
| Trait
|
Alzheimer's disease
|
| Title
|
A genome-wide association study for late-onset Alzheimer's disease using DNA pooling
|
| Risk Allele
|
C
|
| P-val
|
0.0000030000000000000001
|
| Odds Ratio
|
1.63 [1.37-1.95]
|
| PharmGKB | PA164740888 |
| Name | |
| Annotation | A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. (Initial Sample Size: 1,082 cases, 1,239 controls; Replication Sample Size: 1,400 additional controls); (Region: 22q13.33; Reported Gene: CPT1B; Risk Allele: rs727153-C) This variant is associated with Alzheimer's disease. |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:18823527; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Alzheimer Disease |
| Curation Level | Non-Curated |
This SNP is near the gene for lecithin retinol acyltransferase (phosphatidylcholine-retinol O-acetyltransferase) or LRAT, which is involved in Vitamin A metabolism; the risk allele is reportedly G (in dbSNP orientation). [PMID 18823527]
| PharmGKB | PA164740848 |
| Name | |
| Annotation | GWAS results: A genome-wide association study for late-onset Alzheimer's disease using DNA pooling. (Initial Sample Size: 1,082 cases, 1,239 controls; Replication Sample Size: 1,400 additional controls); (Region: 22q13.33; Reported Gene(s): CPT1B; Risk Allele: rs727153-C); (p-value= 0.000003).This variant is associated with Alzheimer's disease. |
| Gene | - |
| Featue | |
| Evidence | PubMed ID:18823527; Web Resource:http://www.genome.gov/gwastudies/ |
| Drugs | |
| Diseases | Alzheimer Disease |
| Curation Level | Non-Curated |
